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      Usefulness and safety of anakinra in refractory Kawasaki disease complicated by coronary artery aneurysm.

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          Abstract

          Kawasaki disease is an acute self-limited vasculitis of unknown aetiology. The prognosis depends mainly on coronary damage. There is no consensus regarding optimal adjunctive therapeutics for refractory forms to treatment by intravenous immunoglobulins and corticosteroids. We report the case of an 18-month-old infant with refractory Kawasaki disease complicated by diffuse aneurysms of coronary arteries and successfully treated by anakinra with partial regression of coronary aneurysms.

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          Author and article information

          Journal
          Cardiol Young
          Cardiology in the young
          Cambridge University Press (CUP)
          1467-1107
          1047-9511
          May 2018
          : 28
          : 5
          Affiliations
          [1 ] 1Pediatric Cardiology,CHU Lille and University of Lille,Lille,France.
          [2 ] 2Pediatric Rheumatology Unit,CHU Lille and University of Lille,Lille,France.
          [3 ] 3Pediatric Emergency unit and Infectious Diseases,CHU Lille and University of Lille,Lille,France.
          Article
          S1047951117002864
          10.1017/S1047951117002864
          29455693
          767e9812-def1-4e99-83fc-32b05486f074
          History

          Refractory Kawasaki disease,anakinra,children,coronary aneurysm

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