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      Persistent carriage and infection by multidrug-resistant Escherichia coli ST405 producing NDM-1 carbapenemase: report on the first Italian cases.

      Journal of Clinical Microbiology
      Anti-Bacterial Agents, pharmacology, Carrier State, diagnosis, microbiology, DNA, Bacterial, genetics, Drug Resistance, Multiple, Bacterial, Electrophoresis, Gel, Pulsed-Field, Escherichia coli, classification, drug effects, enzymology, isolation & purification, Escherichia coli Infections, Genotype, Humans, Italy, Microbial Sensitivity Tests, Molecular Typing, Recurrence, beta-Lactamases, biosynthesis

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          Abstract

          We report on the first detection of the NDM-1 carbapenemase in Italy, in Escherichia coli isolated in October 2009. Prolonged colonization and relapsing infection by NDM-1-positive E. coli were observed in a patient (index case) with an indirect epidemiological link with areas of endemicity. Transient colonization was apparently observed in another patient linked with the index case.

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