Serum Insulin-Like Growth Factors I and II Are Not Affected by Undernutrition in Children with Nonorganic Failure to Thrive

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The aim of our study was to determine the serum levels of IGF-I, IGF-II, and their binding proteins IGFBP-1 and IGFBP-3 in young children 3 months to 2 years of age with nonorganic failure to thrive (NOFTT). 29 children with NOFTT and 32 normal controls were recruited and studied for auxologic and hormonal parameters. The NOFTT group had significantly higher serum concentrations of IGFBP-1 than the control group: 57.7 ± 18 vs. 48 ± 19 µg/l (p < 0.05). IGF-I and IGF-II serum levels were highly correlated to serum IGFBP-3 but there were no differences in the serum IGF-I, IGF-II and IGFBP-3 levels between the groups. We conclude that IGF-I, IGF-II, and IGFBP-3 are not useful for the evaluation of nutritional status in children, under the age of 2 years, with NOFTT.

Related collections

Most cited references 2

Record: found
Abstract: not found
Article: not found

Nutritional regulation of the insulin-like growth factors

J. Thissen (1994)

0 comments Cited 48 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: not found
Article: not found

Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation

A Juul (1995)

0 comments Cited 40 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1998

Publication date (Print): February 1998

Publication date (Electronic): 14 January 1998

Volume: 49

Issue: 2

Pages: 76-79

Affiliations

^a Pediatric Diagnostic and Therapeutic Center, and ^b S. Daniel Abraham International Center for Health and Nutrition, Soroka Medical Center and Ben Gurion University of the Negev, Beer-Sheva, Israel

Article

Publisher ID: 23130 Other ID: Horm Res1998;49:76–79

DOI: 10.1159/000023130

PubMed ID: 9485175

SO-VID: 768abedd-cc77-4ce4-b930-1028dd6615d4

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Page count

Tables: 1, References: 17, Pages: 4

Comments

Comment on this article

scite_

Cited by 1

The impact of obstructive sleep apnea on growth in patients with syndromic and complex craniosynostosis: a retrospective study
Authors: S. Yang, I. M. J. Mathijssen, K. F. M. Joosten

See all cited by

Most referenced authors 39

See all reference authors