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      Transcapillary Oncotic Pressure in the Edema of Congestive Heart Failure

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          Abstract

          Tissue fluid and plasma oncotic pressure levels were measured in an unselected group of 13 patients presenting with congestive heart failure. Patients had a mean serum albumin of 3.6 g/dl ± (SD) 0.35; serum oncotic pressure was 22.23 ± 1.8 mm Hg; tissue fluid (lower leg) oncotic pressure was 0.985 ± 0.34 mm Hg. The oncotic pressure gradient between plasma and tissue fluid was 21.25 Hg ± 1.7. This is about 10 mm Hg greater than △π in normal man. The high value in congestive heart failure is a mechanism to protect against the formation of edema. The possible mechanisms responsible for the formation of edema in congestive heart failure are discussed.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1990
          1990
          10 December 2008
          : 54
          : 1
          : 21-25
          Affiliations
          aNephrology Section, Department of Medicine, Brooklyn VA Medical Center, Brooklyn, N.Y., and bSt. John’s Episcopal Hospital (South Shore Division), Far Rockaway, N.Y., USA
          Article
          185804 Nephron 1990;54:21–25
          10.1159/000185804
          2296340
          7694cc88-9961-4ddc-8d34-a211fc957cef
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 12 May 1989
          Page count
          Pages: 5
          Categories
          Original Paper

          Cardiovascular Medicine,Nephrology
          Edema,Congestive heart failure,Oncotic pressure,Plasma,Interstitial fluid

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