The U.S. Environmental Protection Agency (EPA) has established National Ambient Air
Quality Standards (NAAQS) for six principal air pollutants (“criteria” pollutants):
carbon monoxide (CO), lead (Pb), nitrogen dioxide (NO2), particulate matter (PM) in
two size ranges [< 2.5 μm (PM2.5) and < 10 μm (PM10)], ozone (O3), and sulfur dioxide
(SO2) (U.S. EPA 2010b). Although associations have been identified between these pollutants
and adverse health effects, considerable uncertainty remains regarding a) methods
and approaches to understanding relationships between air pollution and health effects;
b) which components (gas and/or aerosol) and sources are most toxic; c) the mechanisms
of actions of the pollutants and causal relationships; d) effect of confounding factors,
and e) which populations are susceptible {U.S. EPA 2006a (Pb), 2006b (O3), 2008a [NOx
Integrated Science Assessment (ISA)], 2008b (SOx ISA), 2009 (PM), 2010 (CO)}. This
holds true especially for PM, because it is composed of many components with significant
spatial and temporal variation (U.S. EPA 2009). Air pollution and health research
continues to reduce these uncertainties across the source-to-health effects paradigm
as described by the National Research Council (NRC) Research Priorities for Airborne
Particulate Matter, volumes I–IV, (NRC 1998, 1999, 2001, 2004) and the U.S. EPA (2006a,
2006b, 2008a, 2008b, 2009b, 2010a).
Linking air pollution and adverse health effects is complicated and requires expertise
across a range of scientific disciplines—from atmospheric to exposure to health sciences,
as well as inclusion of air quality managers and policy makers who implement and develop
policy to reduce risk from air pollution. Interaction among these groups at different
points in time helps to identify gaps in knowledge and suggest future research directions.
One such opportunity was the international specialty conference “Air Pollution and
Health: Bridging the Gap from Sources to Health Outcomes,” sponsored by the American
Association for Aerosol Research (AAAR 2010). The conference, chaired by myself and
Maria Costantini (Health Effects Institute), was designed to help disseminate and
integrate results from scientific studies that cut across the range of air pollution–
and health-related disciplines of the source-to-health effects continuum. The conference
addressed the science of air pollution and health within a multipollutant framework,
focusing on five key science areas—sources, atmospheric sciences, exposure, dose,
and health effects—as identified by the NRC (1998). Eight key policy-relevant science
questions that integrated across various parts of these science areas formed the basis
of the meeting, and a ninth question addressed the policy implications of the findings
(see Appendix).
This was the AAAR’s third international specialty conference and extended the findings
presented at the AAAR’s first specialty conference “Particulate Matter: Atmospheric
Sciences, Exposure, and the Fourth Colloquium on PM and Human Health,” held in Pittsburgh,
Pennsylvania, in 2003 (Davidson et al. 2005).
Results from the 2010 AAAR Air Pollution and Health conference are being published
in Environmental Health Perspectives (EHP); Air Quality, Atmosphere and Health; Aerosol
Science and Technology; Atmospheric Environment; and Inhalation Toxicology (Solomon
2010).
This issue of EHP includes conference papers on the importance of a multipollutant
approach and of individual components of particulate matter to understanding linkages
between sources and adverse health outcomes, including respiratory and/or cardiovascular
diseases (Ito et al. 2011; Lall et al. 2011; Rohr et al. 2011; Spira-Cohen et al.
2011; Zhou et al. 2011), associated effects, such as inflammation (Alexeeff et al.
2011), and birth outcomes associated with exposures to traffic-related pollution during
gestation (Malmqvist et al. 2011). Several air pollution components and sources were
evaluated, including elemental carbon and secondary organic aerosol, traffic, local
industrial sources, and residential oil and wood burning. Where studied, some effects
varied by season and location over sufficient time (specifically, Detroit, MI; Seattle,
WA; New York, NY), likely due to the influence of different source impacts. In addition,
this issue includes a review of population characteristics related to susceptibility
(Sacks et al. 2011), and an accountability study of the feasibility of hybrid regional–local
modeling to assess health improvements in small communities (Lobdell et al. 2011).