- Record: found
- Abstract: found
- Article: not found
Transition-metal-free lactamization of C(sp3)–H bonds with CO2: facile generation of pyrido[1,2-a]pyrimidin-4-ones
Read this article at
ScienceOpenPublisher
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
A novel carbonylation of C(sp 3)–H bonds in pyridylamines with one atmosphere of CO 2 is reported to synthesize important pyrimidinones in good yields.
Abstract
A novel carbonylation of C(sp 3)–H bonds in pyridylamines with one atmosphere of CO 2 is reported to synthesize important pyrimidinones in good yields. This transition-metal-free and redox-neutral process features the use of a nontoxic carbonyl source, broad substrate scope, good functional group tolerance, facile scalability and easy product derivatization.
