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      Abdominal Adhesions: Current and Novel Therapies

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      Journal of Surgical Research
      Elsevier BV

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          Abstract

          An adhesion occurs when two tissues that normally freely move past each other attach via a fibrous bridge. Abdominal adhesions place a tremendous clinical and financial burden on public health. Adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and, most frequently, small bowel obstruction. A National Hospital Discharge Survey of hospitalizations between 1998 and 2002 reported that 18.1% of hospitalizations were related to abdominal adhesions annually accounting for 948,000 days of inpatient care at an estimated cost of $1.18 billion. This review discusses the current or proposed therapies for abdominal adhesions. While many therapies for abdominal adhesions have been attempted, the need for a definitive therapy to prevent or even reduce abdominal adhesions still exists. Copyright © 2011 Elsevier Inc. All rights reserved.

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          Author and article information

          Journal
          Journal of Surgical Research
          Journal of Surgical Research
          Elsevier BV
          00224804
          January 2011
          January 2011
          : 165
          : 1
          : 91-111
          Article
          10.1016/j.jss.2009.09.015
          20036389
          77408de0-07ce-4d7f-b876-980f1d57fdcf
          © 2011

          https://www.elsevier.com/tdm/userlicense/1.0/

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