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      Morbidity of pertussis in adolescents and adults.

      The Journal of Infectious Diseases

      Adolescent, Adult, Age Distribution, Anti-Bacterial Agents, therapeutic use, Antibiotic Prophylaxis, Asthma, etiology, Canada, epidemiology, Child, Disease Outbreaks, Disease Transmission, Infectious, prevention & control, Female, Hospitalization, Humans, Male, Morbidity, Smoking, adverse effects, Social Change, Whooping Cough, complications, drug therapy, transmission

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          Abstract

          The effect of age on the clinical presentation of pertussis was assessed in 664 adolescent and adult cases. Complications were more frequent in adults than in adolescents (28% vs. 16%). Pneumonia occurred in 2% of patients <30 years old but in 5%-9% of older patients. Urinary incontinence occurred in 34% of women >/=50 years old. Duration of cough, risk of sinusitis, and number of nights with disturbed sleep increased with smoking and asthma. The secondary attack rate in other household members >/=12 years was 11%. Pertussis in secondary case patients was less severe than in index case patients but presented with classic symptoms. The main source of infection in adolescents was schoolmates or friends; in adults it was workplace or their children. Teachers and health care workers had a greater risk of pertussis than did the general population. The burden of disease appears to increase with age, with smoking, and with asthma.

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          Author and article information

          Journal
          10882595
          10.1086/315648

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