Climate change has become a considerable concern for humanity during this anthropocentric era. Scientists believe that the rate of global warming and climate change varies directly with the increase in the concentration of greenhouse gases, particularly carbon dioxide. Urbanization is happening at a higher rate in this era than in any other generation. It was reported that the building sector plays a critical role in the emission of carbon dioxide (CO2) into the atmosphere. Construction of buildings, operation, and utilization of the built environment has led to emissions of a large number of CO2 into the ambient air. Various issues and challenges arise from the building sector in reducing CO2 emissions. The exploitation of non-renewable energy resources, poor building design, and lack of sustainability consideration in urbanization has been holding back CO2 emission mitigation measures in the building sector. Therefore, CO2 emission mitigation plans and schemes are necessary alongside standardized frameworks and guidelines. The strategies to reduce CO2 in the building sector are enforcing standards and policy, conducting impact assessment, adopting low carbon technology, and restricting energy utilization. All stakeholders must play their roles efficiently to reduce CO2 emissions and aid in the fight against climate change.