Effects of different modes exercises on glucose tolerance and insulin sensitivities in adolescents

Abstract

Objective To compare the effects on glucose tolerance and insulin sensitivity between equal isocaloric consumption moderate intensity continuous exercise and high-intensity intermittent exercise in healthy male adolescents, and to provide a reference for a reasonable exercise intervention program to maintain and improve the health level of adolescents.

Methods The 13 subjects from middle schools in Nantong were divided into control group, moderate intensity continuous exercise group (MICE) and high-intensity intermittent exercise group HIIE. The oral glucose tolerance tests were carried out on 13 healthy subjects in all conditions. Meanwhile, the insulin sensitivity index (ISI), total area under the curve ( tAUC) and incremental area under the curve ( iAUC) of glucose as well as insulin were calculated.

Results The tAUC of plasma glucose of MICE and HIIE group decreased by 5.99% ( ES = -0.75) and 9.32% ( ES = -0.86) ( P<0.05) compared to C group, respectively. The tAUC of plasma glucose in HIIE group decreased by 3.54% ( ES = -0.30, P<0.01) compared to MICE group. The tAUC of plasma insulin in MICE and HIIE group was attenuated 4.49% ( ES = -0.64, P<0.01) and 6.79% ( ES =-0.80, P<0.01) compared to C group, respectively. The tAUC of plasma glucose in HIIE group decreased by 2.42% ( ES = -0.30, P<0.01) compared to MICE group. The iAUC of plasma glucose in MICE and HIIE group decreased by 25.52% ( ES = -0.57, P<0.01) and 35.82% ( ES = -0.73, P<0.01) compared to C group, respectively. The iAUC of plasma glucose in HIIE group decreased by 13.83% ( ES = -0.16, P<0.05) compared to MICE group. The iAUC of plasma insulin in MICE and HIIE group descended by 7.14% ( ES = -0.67, P<0.01) and 10.18%( ES =-0.75, P<0.01) compared to C group, respectively. The iAUC of plasma insulin in HIIE group decreased by 3.27% ( ES = 0.21, P<0.05) compared to MICE group. The ISI of MICE and HIIE group increased by 1.65% ( ES = 0.15, P>0.05) and 4.72% ( ES = 0.25, P<0.01) compared to C group, respectively. There was no significantly difference in ISI between MICE and HIIE group.

Conclusion The intervention effects on the level of glucose, insulin and insulin sensitivity of high intensity intermittent exercise is better than moderate intensity continuous exercise among adolescents.

Abstract

【摘要】 目的 比较相等能量消耗的髙强度间歇性运动和中等强度持续性运动对健康青少年糖耐量和胰岛素敏感 性的影响。为制定维持与增进青少年健康水平的合理运动干预方案提供参考。 方法 通过现场宣讲的方式在南通市某中 学纳人 13 名被试, 分为安静对照组 (C)、中等强度持续性运动组 (MICE) 和髙强度间歇性运动组 (HIIE) 后进行口服葡萄糖 耐量试验, 并计算胰岛素敏感指数、葡萄糖和胰岛素的总曲线下面积 (MUC)、曲线下面积增量 ( iAUC)。 结果 与 C 组相 比, MICE 组和 HIIE 组葡萄糖 tAUC 值分别下降了 5.99%( ES =-0.75)和 9.32%( ES = -0.86) ( P<0.05); 与 MICE 组相比, HI- IE 组葡萄糖 tAUC值下降了 3.54%( ES =-0.30, _ P<0.01)。与C组相比, MICE 组和 HIIE 组胰岛素 MUC 分别下降了 4.49% ( ES = -0.64, P<0.01)和 6.79% ( ES =-0.80, P<0.01); 与 MICE 组相比, HIIE 组胰岛素 tAUC 下降了 2.42% ( ES = -0.30, P< 0.01)。与 C 组相比, MICE 组和 HIIE 组血糖 iAUC 值分别下降了 25.52% ( ES = -0.57, P<0.01)和 35.82.% ( ES = -0.73, P< 0.01); 与 MICE 相比, HIIE 组血糖 iAUC值下降了 13.83% ( ES = -0.16, P<0.05)。与C组相比, MICE 组和 HIIE 组胰岛素 iAUC 值分别下降了 7.14% ( ES = -0.67, P<0.01) 和 10.18% ( ES =-0.75, P<0.01); 与 MICE 组相比, HIIE 组血浆胰岛素 iAUC 值下降了3.27%( ES = 0.21, P<0.05)。与 C 组相比, MICE 组和 HIIE 组的 ISI 水平分别上升了 1.65% ( ES = 0.15, P>0.05) 和 4.72% ( ES = 0.25, P<0.01), MICE 组和 HIIE 组间差异无统计学意义 ( ES = 0.04, P<0.05)。 结论 髙强度间歇性运动对健康 青少年血糖、胰岛素和胰岛素敏感性的干预效应优于中等强度持续性运动。