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      Highly sensitive graphene biosensors based on surface plasmon resonance

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      Optics Express

      The Optical Society

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          Abstract

          A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene.

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          Most cited references 17

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          Fine structure constant defines visual transparency of graphene.

          There are few phenomena in condensed matter physics that are defined only by the fundamental constants and do not depend on material parameters. Examples are the resistivity quantum, h/e2 (h is Planck's constant and e the electron charge), that appears in a variety of transport experiments and the magnetic flux quantum, h/e, playing an important role in the physics of superconductivity. By and large, sophisticated facilities and special measurement conditions are required to observe any of these phenomena. We show that the opacity of suspended graphene is defined solely by the fine structure constant, a = e2/hc feminine 1/137 (where c is the speed of light), the parameter that describes coupling between light and relativistic electrons and that is traditionally associated with quantum electrodynamics rather than materials science. Despite being only one atom thick, graphene is found to absorb a significant (pa = 2.3%) fraction of incident white light, a consequence of graphene's unique electronic structure.
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            Nanostructured plasmonic sensors.

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              Exploitation of Localized Surface Plasmon Resonance

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                Author and article information

                Journal
                OPEXFF
                Optics Express
                Opt. Express
                The Optical Society
                1094-4087
                2010
                2010
                June 21 2010
                July 05 2010
                : 18
                : 14
                : 14395
                Article
                10.1364/OE.18.014395
                20639924
                © 2010

                Molecular medicine, Neurosciences

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