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      Letter to the editor on “Stents and surgical interventions in the palliation of gastric outlet obstruction: a systematic review”

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      Endoscopy International Open
      © Georg Thieme Verlag KG

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          Abstract

          We read with interest the paper, “Stents and surgical interventions in the palliation of gastric outlet obstruction: a systematic review” by Minata MK et al, which appeared in Endoscopy International Open (2016; 4: E1158 – 1170) 1 . The Authors should be congratulated for an extensive and careful review. In recent studies, we prospectively analyzed the clinical outcomes of 72 patients 2 3 and we came to similar conclusions. We have abandoned the use of covered stents. Distal migration of a covered stent can lead to serious consequences and a stent rarely can be retrieved endoscopically 4 . Endoscopic stenting offers many advantages in comparison to surgery: shorter hospital stay, faster return to oral intake, a less invasive procedure. However, life expectance may be longer than 1 year in some patients with malignant gastric outlet obstruction, particularly those with distal gastric cancer or gastric obstruction from metastatic disease. In this selected group of patients, food obstruction is common. The reason for it in rare cases derives from tumor in-growth within the stent; in the majority of patients, food obstruction is secondary to dismotility of the pyloric region. The dismotility depends on many factors, including nerve infiltration by the tumor. Food obstruction is not easily diagnosed. The stomach can enlarge significantly before vomiting occurs. Stomach dilation can lead to nausea, discomfort, and dyspnea, symptoms that easily can be attributed to the cancer itself. For all these reasons, patients who have endoscopic stenting in this clinical setting should have a very careful follow-up with repeated endoscopies and computed tomography scan. This careful follow-up may not be well tolerated by a patient whose general condition is slowly deteriorating or for his or her family. Laparoscopic surgery can be performed with minimal discomfort for patients and it should be seriously considered in patients whose conditions are generally acceptable. Before such a procedure, the patient and family should be consulted and all positive and negative aspects of the surgery should be thoroughly explained, leaving them to choose the preferred treatment.

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          Most cited references4

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          Covered versus uncovered self-expandable metallic stents for palliation of malignant pyloric obstruction in gastric cancer patients: a randomized, prospective study.

          Self-expandable metallic stents (SEMSs) provide effective palliation of malignant pyloric obstruction in patients with inoperable gastric cancer. To compare the effectiveness and side effects of covered and uncovered SEMSs for the palliation of malignant pyloric obstruction. Prospective, randomized, single-center study. Tertiary-care cancer center hospital. This study involved 80 patients with pyloric obstruction related to inoperable gastric cancer. Covered or uncovered SEMS placement. Technical and clinical success rates as well as the patency rate at 8 weeks after placement. Both groups had a technical success rate of 100% with no immediate complications. Both groups also had comparable clinical success rates (covered SEMS, 95% [38 of 40] and uncovered SEMS, 90% [36 of 40], P = .68) and 8-week patency rates (covered SEMS, 61.3% [19 of 31] and uncovered SEMS, 61.1% [22 of 36], P > .99). Stent migration within 8 weeks was more common in the covered SEMS group (25.8% [8 of 31]) than in the uncovered SEMS group (2.8% [1 of 36], P = .009), whereas re-stenosis because of tumor ingrowth was more common in the uncovered SEMS group (25.0% [9 of 36] vs 0% [0 of 31] in the covered SEMS group, P = .003). Overall patient survival and stent patency did not differ between groups (P = .27 and 0.61 by log-rank test, respectively). The study population was limited to gastric cancer patients, and stent designs were changed in the midst of the study period. Both the covered and uncovered SEMSs are effective and have comparable 8-week patency in patients with malignant pyloric obstruction, despite different patterns of late stent failure. Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
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            Endoscopic stenting for gastric outlet obstruction in patients with unresectable antro pyloric cancer. Systematic review of the literature and final results of a prospective study. The point of view of a surgical group.

            The authors report the final results of a prospective single-center randomized study whose aim was to compare the endoscopic placement of self-expandable stents with open surgical gastroenterostomy to relieve gastric outlet obstruction (GOO) in patients with advanced antropyloric adenocarcinoma. A systematic review of the medical literature from December 1999 to December 2011 was carried out to determine the results of endoscopic stenting in patients with GOO from unresectable primary cancer of the antropyloric region.
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              Factors Leading to Improved Results for Endoscopic Stenting for Metastatic Antropyloric Adenocarcinoma. A Comparison with Gastrojejunostomy.

              Controversies exist about the optimal palliative management for patients with metastatic antropyloric adenocarcinoma. The aim of this study was to analyse the clinical outcome for patients with gastric outlet obstruction syndrome and metastatic antropyloric adenocarcinoma, who underwent endoscopic stenting or open gastrojejunostomy, in a prospective not randomised study.
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                Author and article information

                Journal
                Endosc Int Open
                Endosc Int Open
                10.1055/s-00025476
                Endoscopy International Open
                © Georg Thieme Verlag KG (Stuttgart · New York )
                2364-3722
                2196-9736
                July 2017
                06 July 2017
                : 5
                : 7
                : E652
                Affiliations
                Isituto Pietro Valdoni, University of Rome- Sapienza, Italy
                Author notes
                Corresponding author Antonio V Sterpetti, MD, FACS, FRCS Viale del Policlinico 00167 RomeItaly+0039-6-49972245 antonio.sterpetti@ 123456uniroma1.it
                Article
                10.1055/s-0043-112496
                5500115
                7803342d-2553-4580-bb0a-8a9509cf8ced
                © Thieme Medical Publishers
                History
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