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      Montelukast inhibits matrix metalloproteinases expression in atherosclerotic rabbits.

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          Abstract

          Matrix metalloproteinases (MMPs) play important roles in the development and destabilization of atherosclerotic plaques. It is known that montelukast inhibits neointimal hyperplasia. However, the underlying mechanisms for the inhibitory effects of montelukast on neointimal formation have been poorly defined.

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          Author and article information

          Journal
          Cardiovasc Drugs Ther
          Cardiovascular drugs and therapy
          Springer Nature
          1573-7241
          0920-3206
          Dec 2009
          : 23
          : 6
          Affiliations
          [1 ] Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, 305# East Zhongshan Road, Nanjing, 210002, Jiangsu Province, People's Republic of China.
          Article
          10.1007/s10557-009-6211-6
          19998057
          78066dbd-c6ae-4378-800f-e0776c90f9dd
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