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      The psychiatric side-effects of rimonabant.

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          Abstract

          Experimental evidence has suggested that drugs that enhance cannabinoid type-1 (CB1) receptor activity may induce anxiolytic and antidepressant effects, whilst the opposite has been reported with antagonists. Thus, the objective of the present review is to discuss the potential psychiatric side-effects of CB1 receptor antagonists, such as rimonabant, which has been recently marketed in several countries for the treatment of smoking cessation, obesity and associated metabolic disorders.

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          Author and article information

          Journal
          Braz J Psychiatry
          Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
          FapUNIFESP (SciELO)
          1516-4446
          1516-4446
          Jun 2009
          : 31
          : 2
          Affiliations
          [1 ] Department of Pharmacology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
          Article
          S1516-44462009000200012
          10.1590/s1516-44462009000200012
          19578688
          780edbd6-19d0-4110-b883-55566f9f522c
          History

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