Linkage Analysis in Man by Somatic Cell Genetics

RUDDLE, FRANK H.

doi:10.1038/242165a0

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Linkage Analysis in Man by Somatic Cell Genetics

Author(s): FRANK H. RUDDLE

Publication date Created: March 1973

Publication date (Print): March 1973

Journal: Nature

Publisher: Springer Nature

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Chromosomal Localization of Mouse Satellite DNA

M L Pardue, J Gall (1970)

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SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Michael J. Littlefield (1964)

When two clonal lines of mouse fibroblasts, each containing a drug-resistant marker, are grown together for 4 days, hybrid cells can be detected by selective conditions. These hybrid cells are presumed to be the result of mating. By the same method evidence can be obtained which suggests that mating may be followed by segregation.