14
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be non-inferior to fractional flow reserve (FFR) for major adverse cardiovascular events at one year; however, iFR is limited by sensitive landmarking of the pressure waveform, and the assumption that maximal flow and minimal resistance occur during a fixed period of diastole. We sought to validate the resting full-cycle ratio (RFR), a novel non-hyperaemic index of coronary stenosis severity based on unbiased identification of the lowest distal coronary pressure to aortic pressure ratio (Pd/Pa), independent of the ECG, landmark identification, and timing within the cardiac cycle.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: found
          • Article: found

          Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI

          Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone. It is unknown whether the instantaneous wave-free ratio (iFR), an alternative measure that does not require the administration of adenosine, will offer benefits similar to those of FFR.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Multicenter core laboratory comparison of the instantaneous wave-free ratio and resting Pd/Pa with fractional flow reserve: the RESOLVE study.

            This study sought to examine the diagnostic accuracy of the instantaneous wave-free ratio (iFR) and resting distal coronary artery pressure/aortic pressure (Pd/Pa) with respect to hyperemic fractional flow reserve (FFR) in a core laboratory-based multicenter collaborative study.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Comparison of Different Diastolic Resting Indexes to iFR: Are They All Equal?

              Pressure measurement for the duration of the wave-free period (WFP) is considered essential for resting-state physiological assessment of coronary stenosis severity using the instantaneous wave-free ratio (iFR).
                Bookmark

                Author and article information

                Journal
                EuroIntervention
                EuroIntervention
                Europa Digital & Publishing
                1774-024X
                September 2018
                September 2018
                : 14
                : 7
                : 806-814
                Article
                10.4244/EIJ-D-18-00342
                29790478
                7820d848-19b2-40d9-8bd7-bdf9720d25fe
                © 2018
                History

                Comments

                Comment on this article