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      High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial.

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          Abstract

          Enteral administration of immune-modulating nutrients (eg, glutamine, omega-3 fatty acids, selenium, and antioxidants) has been suggested to reduce infections and improve recovery from critical illness. However, controversy exists on the use of immune-modulating enteral nutrition, reflected by lack of consensus in guidelines.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          Aug 06 2014
          : 312
          : 5
          Affiliations
          [1 ] Gelderse Vallei Hospital, Ede, the Netherlands.
          [2 ] Groupe Hôpital Pellegrin - CHU Bordeaux, Bordeaux, France.
          [3 ] Universitätsklinikum Leipzig, Germany.
          [4 ] Heinrich-Braun-Klinikum, Zwickau, Germany.
          [5 ] Klinikum Neuperlach, Munich, Germany.
          [6 ] Klinikum St Georg, Leipzig, Germany.
          [7 ] Ghent University Hospital, Ghent, Belgium.
          [8 ] Hôpital Universitaire Albert Michallon, Grenoble, France.
          [9 ] Medisch Centrum Alkmaar, Alkmaar, the Netherlands.
          [10 ] Charité Universitätsmedizin Berlin, Germany.
          [11 ] Erasme University Hospital, Université libre de Bruxelles, Brussels, Belgium.
          [12 ] Hôpital Antoine-Béclère, Clamart, France.
          [13 ] Nutricia Advanced Medical Nutrition, Nutricia Research, Utrecht, the Netherlands.
          Article
          1892247
          10.1001/jama.2014.7698
          25096691

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