High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial.

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Abstract

Enteral administration of immune-modulating nutrients (eg, glutamine, omega-3 fatty acids, selenium, and antioxidants) has been suggested to reduce infections and improve recovery from critical illness. However, controversy exists on the use of immune-modulating enteral nutrition, reflected by lack of consensus in guidelines.

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Journal

Journal ID (iso-abbrev): JAMA

Title: JAMA

Publisher: American Medical Association (AMA)

ISSN (Electronic): 1538-3598

ISSN (Print): 0098-7484

Publication date (Electronic): Aug 06 2014

Volume: 312

Issue: 5

Affiliations

[1 ] Gelderse Vallei Hospital, Ede, the Netherlands.

[2 ] Groupe Hôpital Pellegrin - CHU Bordeaux, Bordeaux, France.

[3 ] Universitätsklinikum Leipzig, Germany.

[4 ] Heinrich-Braun-Klinikum, Zwickau, Germany.

[5 ] Klinikum Neuperlach, Munich, Germany.

[6 ] Klinikum St Georg, Leipzig, Germany.

[7 ] Ghent University Hospital, Ghent, Belgium.

[8 ] Hôpital Universitaire Albert Michallon, Grenoble, France.

[9 ] Medisch Centrum Alkmaar, Alkmaar, the Netherlands.

[10 ] Charité Universitätsmedizin Berlin, Germany.

[11 ] Erasme University Hospital, Université libre de Bruxelles, Brussels, Belgium.

[12 ] Hôpital Antoine-Béclère, Clamart, France.

[13 ] Nutricia Advanced Medical Nutrition, Nutricia Research, Utrecht, the Netherlands.

Article

Publisher Item ID: 1892247

DOI: 10.1001/jama.2014.7698

PubMed ID: 25096691

SO-VID: 7833c041-5b95-41b7-9ce9-0abcee9e2dc0

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