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      The Basic Science of Wound Healing

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          Abstract

          Understanding wound healing today involves much more than simply stating that there are three phases: "inflammation, proliferation, and maturation." Wound healing is a complex series of reactions and interactions among cells and "mediators." Each year, new mediators are discovered and our understanding of inflammatory mediators and cellular interactions grows. This article will attempt to provide a concise report of the current literature on wound healing by first reviewing the phases of wound healing followed by "the players" of wound healing: inflammatory mediators (cytokines, growth factors, proteases, eicosanoids, kinins, and more), nitric oxide, and the cellular elements. The discussion will end with a pictorial essay summarizing the wound-healing process.

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          Author and article information

          Journal
          Plastic and Reconstructive Surgery
          Plastic and Reconstructive Surgery
          Ovid Technologies (Wolters Kluwer Health)
          0032-1052
          2006
          June 2006
          : 117
          : SUPPLEMENT
          : 12S-34S
          Article
          10.1097/01.prs.0000225430.42531.c2
          16799372
          784aa124-c652-414c-b23a-c9a9616e12e6
          © 2006
          History

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