For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
23
views
21
references
 Top references
cited by
5
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      832
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: not found

      Effect of NaCl on Heat Resistance, Antibiotic Susceptibility, and Caco-2 Cell Invasion of Salmonella

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          This study evaluated the effects of NaCl on heat resistance, antibiotic susceptibility, and Caco-2 cell invasion of Salmonella. Salmonella typhimurium NCCP10812 and Salmonella enteritidis NCCP12243 were exposed to 0, 2, and 4% NaCl and to sequential increase of NaCl concentrations from 0 to 4% NaCl for 24 h at 35°C. The strains were then investigated for heat resistance (60°C), antibiotic susceptibility to eight antibiotics, and Caco-2 cell invasion efficiency. S. typhimurium NCCP10812 showed increased thermal resistance ( P < 0.05) after exposure to single NaCl concentrations. A sequential increase of NaCl concentration decreased ( P < 0.05) the antibiotic sensitivities of S. typhimurium NCCP10812 to chloramphenicol, gentamicin, and oxytetracycline. NaCl exposure also increased ( P < 0.05) Caco-2 cell invasion efficiency of S. enteritidis NCCP12243. These results indicate that NaCl in food may cause increased thermal resistance, cell invasion efficiency, and antibiotic resistance of Salmonella.

          Related collections

          Most cited references21

          • Record: found
          • Abstract: found
          • Article: not found

          Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase.

          Regine Hengge (2002)
          The sigma(S) (RpoS) subunit of RNA polymerase is the master regulator of the general stress response in Escherichia coli and related bacteria. While rapidly growing cells contain very little sigma(S), exposure to many different stress conditions results in rapid and strong sigma(S) induction. Consequently, transcription of numerous sigma(S)-dependent genes is activated, many of which encode gene products with stress-protective functions. Multiple signal integration in the control of the cellular sigma(S) level is achieved by rpoS transcriptional and translational control as well as by regulated sigma(S) proteolysis, with various stress conditions differentially affecting these levels of sigma(S) control. Thus, a reduced growth rate results in increased rpoS transcription whereas high osmolarity, low temperature, acidic pH, and some late-log-phase signals stimulate the translation of already present rpoS mRNA. In addition, carbon starvation, high osmolarity, acidic pH, and high temperature result in stabilization of sigma(S), which, under nonstress conditions, is degraded with a half-life of one to several minutes. Important cis-regulatory determinants as well as trans-acting regulatory factors involved at all levels of sigma(S) regulation have been identified. rpoS translation is controlled by several proteins (Hfq and HU) and small regulatory RNAs that probably affect the secondary structure of rpoS mRNA. For sigma(S) proteolysis, the response regulator RssB is essential. RssB is a specific direct sigma(S) recognition factor, whose affinity for sigma(S) is modulated by phosphorylation of its receiver domain. RssB delivers sigma(S) to the ClpXP protease, where sigma(S) is unfolded and completely degraded. This review summarizes our current knowledge about the molecular functions and interactions of these components and tries to establish a framework for further research on the mode of multiple signal input into this complex regulatory system.
          Article 0 comments Cited 105 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Non-typhoidal Salmonella infections in pigs: a closer look at epidemiology, pathogenesis and control.

            F. Haesebrouck, F Boyen, F. Pasmans … (2008)
            Contaminated pork is an important source of Salmonella infections in humans. The increasing multiple antimicrobial resistance associated with pork-related serotypes such as Salmonella Typhimurium and Salmonella Derby may become a serious human health hazard in the near future. Governments try to anticipate the issue of non-typhoidal Salmonella infections in pork by starting monitoring programmes and coordinating control measures worldwide. A thorough knowledge of how these serotypes interact with the porcine host should form the basis for the development and optimisation of these monitoring and control programmes. During recent years, many researchers have focussed on different aspects of the pathogenesis of non-typhoidal Salmonella infections in pigs. The present manuscript reviews the importance of pigs and pork as a source for salmonellosis in humans and discusses commonly accepted and recent insights in the pathogenesis of non-typhoidal Salmonella infections in pigs, with emphasis on Salmonella Typhimurium, and to relate this knowledge to possible control measures.
            Article 0 comments Cited 76 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Emergence of multidrug-resistant Salmonella enterica serotype typhimurium DT104 infections in the United States.

              Laura Glynn, Nadia Mokhtar, C Bopp … (1998)
              Strains of salmonella that are resistant to antimicrobial agents have become a worldwide health problem. A distinct strain of Salmonella enterica serotype typhimurium, known as definitive type 104 (DT104), is resistant to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline and has become a major cause of illness in humans and animals in Europe, especially the United Kingdom. To characterize typhimurium DT104 infections in the United States, we analyzed data collected by local and state health departments and public health laboratories between 1979 and 1996 in national surveys of the antimicrobial-drug resistance of salmonella. Selected typhimurium isolates with the five-drug pattern of resistance were phage typed. The prevalence of typhimurium isolates with the five-drug pattern of resistance increased from 0.6 percent in 1979-1980 to 34 percent in 1996. In 1994-1995, such isolates were identified in samples from 36 of the 46 surveillance sites (78 percent). Thirty-nine of 43 typhimurium isolates with the five-drug pattern of resistance identified in 1994-1995 and 1996 were phage type DT104 or a closely related phage type. Multidrug-resistant typhimurium DT104 has become a widespread pathogen in the United States. More prudent use of antimicrobial agents in farm animals and more effective disease prevention on farms are necessary to reduce the dissemination of multidrug-resistant typhimurium DT104 and to slow the emergence of resistance to additional agents in this and other strains of salmonella.
              Article 0 comments Cited 73 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Biomed Res Int
                Journal ID (iso-abbrev): Biomed Res Int
                Journal ID (publisher-id): BMRI
                Title: BioMed Research International
                Publisher: Hindawi Publishing Corporation
                ISSN (Print): 2314-6133
                ISSN (Electronic): 2314-6141
                Publication date (Print): 2013
                Publication date (Electronic): 8 July 2013
                Volume: 2013
                Electronic Location Identifier: 274096
                Affiliations
                1Department of Food and Nutrition, Sookmyung Women's University, Seoul 140-742, Republic of Korea
                2National Institute of Animal Science, RDA, Suwon, Gyeonggi 441-706, Republic of Korea
                3Department of Oral Microbiology, College of Dentistry, Wonkwang University, Iksan, Chonbuk 570-749, Republic of Korea
                Author notes
                *Kyoung-Hee Choi: kheechoi@ 123456wonkwang.ac.kr and

                Academic Editor: Jacek Bania

                Article
                DOI: 10.1155/2013/274096
                PMC ID: 3722778
                PubMed ID: 23936782
                SO-VID: 787f9f9e-0e54-4356-8c5d-2e69b3f5e116
                Copyright © Copyright © 2013 Hyunjoo Yoon et al.
                License:

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 15 April 2013
                Date accepted : 6 June 2013
                Categories
                Subject: Research Article

                Data availability:

                Comments

                Comment on this article

                scite_

                Similar content832

                See all similar

                Cited by3

                See all cited by

                Most referenced authors174

                See all reference authors