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Abstract
In this piece of work, a fiber optic sensor has been fabricated and characterized
using surface plasmon resonance for dextrose sensing. The concentration range used
in this study is for diagnosing the cases of hypoglycaemia especially in suppression
tests of insulinoma. Insulinoma is a medical case in which the person is recognized
being hypoglycaemic with the blood dextrose level falling down to 2.2mM or less. Thus,
the sensor has been characterized for the dextrose concentration range of 0 mM-10mM
including the cases of normal blood dextrose range. Coatings of silver layer and zinc
oxide nanorods have been carried out on the bare core fiber with a dual role of zinc
oxide followed by immobilization of glucose oxidase. A three stage optimization procedure
has been adopted for the best performance of the sensor. Absorbance spectra have been
plotted and peak absorbance wavelengths have been extracted for each concentration
chosen along with the sensitivities. The results have been made conclusive with control
experiments. The probe has also been tested on sample having blood serum to check
the reliability of the sensor. The sensor shows better selectivity and response time
along with its real time applications, online monitoring, remote sensing and reusability.