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      Editorial for the Special Issue on Micro/Nano-Chip Electrokinetics, Volume II

      editorial
      1 , * , 2
      Micromachines
      MDPI

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          Abstract

          There has been a rapidly increasing interest in the use of micro/nanofluidics to develop various point-of-care technologies for global health [1,2]. Electrokinetics is often the method of choice in these micro/nano-chips for an accurate transport and manipulation of fluids and samples [3,4]. This special issue in Micromachines is the continuation of our successful first volume on Micro/Nano-Chip Electrokinetics [5]. It consists of 22 contributions, which cover multiple aspects of electrokinetics related phenomena for various chemical and biological applications. We divide these papers into three primary categories and summarize them briefly below. 1. Linear Electrokinetic Phenomena (Seven Papers) Fluid electroosmosis and particle electrophoresis are linear electrokinetic phenomena, and are proportional and parallel to the applied electric field [3,4]. Electroosmotic flow in micro/nanochannels can be significantly affected by the fluid rheological properties in addition to the wall properties. Guo and Qi [6] obtained an analytical solution of the electroosmotic peristaltic flow of viscoelastic fluids through a cylindrical microchannel using the fractional Jeffrey’s constitutive model. Choi et al. [7] carried out a finite element analysis of the electroosmotic flow of power-law fluids in a rectangular microchannel with asymmetric wall zeta potentials. They later [8] reported an approximate analytical solution to a similar flow in a slit microchannel. Mei et al. [9] studied the electroosmotic flow of a linear Phan–Thien–Tanner fluid in a nanoslit by solving numerically the nonlinear Poisson–Nernst–Planck equations. Matías et al. [10] presented a perturbation analysis of Joule heating effects on electroosmotic flow in a microcapillary tube filled with immiscible Newtonian and power-law fluids. Lu et al. [11] used a molecular dynamics simulation to study the electroosmotic flow in rough nanochannels, with particular attention to the fluid–solid interactions. Lim et al. [12] developed a technique to fabricate microchannels with black silicon nanostructures for a controllable suppression of electroosmotic flow. 2. Nonlinear Electrokinetic Phenomena (Eight Papers) Nonlinear electrokinetic phenomena occur because of the action of electric field on an electrically induced dipole (i.e., dielectrophoresis or DEP) or free charge (e.g., induced charge electrokinetic phenomena and electrothermal flow). Akshay et al. [13] demonstrated significantly enhanced particle focusing and enrichment by the use of three-dimensional reservoir-based dielectrophoresis (rDEP) at the reservoir–microchannel junction. Zhao et al. [14] used a volumetric polarization and integration method to investigate the mechanisms for their observed tumbling motion of pearl chains and alignment of ellipsoidal particles. Both phenomena were found to be governed by the particle–particle interactions under DEP. Ji et al. [15] reported a direct numerical simulation of similar dielectrophoretic interactions between deformable particles. Liu et al. [16] proposed a method of bipolar field-effect control of direct current electroosmosis for multifunctional sample handling. Later, Tao et al. [17] used a similar idea to design nanofluidic ion diodes for field-effect control of ion current. Hu et al. [18] utilized the stirring fluid motion of induced charge electroosmotic flow over a floating gate electrode to improve the binding efficiency of microfluidic heterogeneous immunoassays. Ren et al. [19] explored the feasibility of using alternating current electric field-induced nonlinear electroosmosis next to sharp dielectric corners for on-chip mixing. Liu et al. [20] studied the electrode cooling effect on the travelling wave electrothermal flow in rotating electric fields. 3. Other Electric-Field-Mediated Phenomena (Seven Papers) Song et al. [21] reported a numerical study of the electric-magnetic regulation of the heat convection between an electrolyte solution and microchannel walls for potential applications to microelectronics cooling. Shen et al. [22] demonstrated the use of optimized electrical driving waveforms to reduce the fringe phenomena in electrophoretic display. Zhang et al. [23] reported an on-chip impedance sensor that is capable of detecting both rigid particles and soft droplets/bubbles in hydraulic oil in an inductive and a capacitive mode, respectively. Yazdanshenas et al. [24] developed a microfluidic Kelvin water dropper that can generate high-voltage electricity through water dripping and also used their device to replace the high-voltage power supply in electrowetting. Hu et al. [25] demonstrated a microfluidic mixer design that utilizes amplified Marangoni chaotic advection induced by alternating current electrowetting of a metal droplet. Ahmed and Kim [26] presented a numerical parametric study of electroosmotic micro-mixers with heterogeneously charged surface patches on channel walls. In another study, Chen et al. [27] proposed and numerically verified the use of embedded asymmetric electrode arrays on microchannel walls to generate vortices for mixing enhancement. We would like to express our sincere thanks to all of the contributors to this Special Issue. We also appreciate the time and efforts from all the reviewers, without which this Special issue would not be possible.

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          Point-of-care testing (POCT) diagnostic systems using microfluidic lab-on-a-chip technologies

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            Analytical Solution of Electro-Osmotic Peristalsis of Fractional Jeffreys Fluid in a Micro-Channel

            The electro-osmotic peristaltic flow of a viscoelastic fluid through a cylindrical micro-channel is studied in this paper. The fractional Jeffreys constitutive model, including the relaxation time and retardation time, is utilized to describe the viscoelasticity of the fluid. Under the assumptions of long wavelength, low Reynolds number, and Debye-Hückel linearization, the analytical solutions of pressure gradient, stream function and axial velocity are explored in terms of Mittag-Leffler function by Laplace transform method. The corresponding solutions of fractional Maxwell fluid and generalized second grade fluid are also obtained as special cases. The numerical analysis of the results are depicted graphically, and the effects of electro-osmotic parameter, external electric field, fractional parameters and viscoelastic parameters on the peristaltic flow are discussed.
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              “Connecting worlds – a view on microfluidics for a wider application”

                Author and article information

                Journal
                Micromachines (Basel)
                Micromachines (Basel)
                micromachines
                Micromachines
                MDPI
                2072-666X
                02 August 2018
                August 2018
                : 9
                : 8
                : 383
                Affiliations
                [1 ]Department of Mechanical Engineering, Clemson University, Clemson, SC 29634, USA
                [2 ]Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, VA 23529, USA; SQian@ 123456odu.edu
                Author notes
                [* ]Correspondence: xcxuan@ 123456clemson.edu
                Author information
                https://orcid.org/0000-0003-0158-4186
                Article
                micromachines-09-00383
                10.3390/mi9080383
                6187532
                78ad64dc-4c62-4137-9b67-07298f74893b
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 25 July 2018
                : 30 July 2018
                Categories
                Editorial

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