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      Dinâmica folicular em cabras da raça Toggenburg em lactação tratadas ou não com somatotropina bovina recombinante Translated title: Follicular dynamics of lactating Toggenburg does treated with recombinant bovine somatotropin

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          Abstract

          Avaliou-se o efeito da injeção de somatotropina bovina recombinante (r-bST) sobre o ciclo estral de cabras. Foram utilizadas 24 fêmeas da raça Toggenburg, distribuídas em dois tratamentos: T1 (n=12), cabras tratadas com r-bST; e T2 (n=12), cabras tratadas com solução salina (controle). A partir da primeira injeção do tratamento, acompanhou-se o ciclo dos animais em estro até o estro subseqüente. O comprimento médio do ciclo estral e o período interovulatório não diferiram (P>0,05) entre os tratamentos. Foram verificados ciclos estrais de duas, três e quatro ondas de crescimento folicular. Não houve diferença (P>0,05) entre os tratamentos quanto ao número de ondas do ciclo estral. O número de folículos detectados com diâmetro >3mm nas cabras do T1 foi maior (P<0,05) que naquelas do T2 nos ciclos com duas (15,3±1,2 x 8,1±2,0), três (12,2±0,8 x 8,3±1,9) e quatro (12,7±1,7 x 8,8±2,5) ondas. O folículo dominante da segunda onda foi menor (P<0,05) que o da primeira e terceira ondas e também menor que o da onda ovulatória tanto para T1 quanto para T2. A concentração sérica de progesterona durante o ciclo estral não foi influenciada pelos tratamentos com r-bST (P>0,05). A r-bST não alterou a dinâmica folicular de cabras lactantes da raça Toggenburg, mas promoveu o aumento do número de folículos recrutados ³3mm durante o ciclo estral.

          Translated abstract

          The effect of the r-bST injection was evaluated on the goats estrous cycles. Twenty-four Toggenburg does were used in two treatments: T1 (n=12) treated with r-bST; and T2 (n=12) treated with saline solution (control). After the first r-bST injection, the estrous cycles were checked between two estrus. The estrous cycle length and interovulatory period of the goats did not differ between treatments (P>0.05). Estrous cycles with two, three and four waves of follicular growth were observed. The number of waves during the estrous cycle were not affected by the r-bST treatment (P>0.05). The number of 3mm follicles was different between T1 and T2 (P<0.05) for estrous cycles with two (15.3±1.2 x 8.1±2.0), three (12.2±0.8 x 8.3±1.9) or four (12.7±1.7 x 8.8±2.5) waves. The dominant follicle of the second wave was smaller (P<0.05) than the one of the first and third waves and smaller than the one of the ovulatory wave. The progesterone concentration during the estrous cycle of the animals did not differ (P>0.05) between treatments. The r-bST did not affect the ovarian response during the estrous cycle. The r-bST not affected the follicular dynamic of Toggenburg lactating does, but increased the number of emerging follicles >3mm during the estrous cycle.

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          Most cited references27

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          Bovine somatotropin and lactation: from basic science to commercial application.

          D.E Bauman (1999)
          Bovine somatotropin (bST) results in increased milk yield and an unprecedented improvement in efficiency. Beginning in the 1930s to present day, investigations have examined animal-related factors such as nutrition, bioenergetics, metabolism, health and well being and consumer-related factors such as milk quality, manufacturing characteristics, and product safety. Overall, bST is a homeorhetic control involved in orchestrating many physiological processes. Direct effects involve adaptations in many tissues and the metabolism of all nutrient classes--carbohydrates, lipids, protein, and minerals. Mechanisms include alterations in key enzymes, intracellular signal transduction systems, and tissue response to homeostatic signals. Indirect effects involve the mammary gland and are thought to be mediated by the insulin-like growth factor (IGF) system. Specific changes include increased cellular rates of milk synthesis and enhanced maintenance of secretory cells. Indirect effects are modulated by environment and management factors, especially nutritional status. This modulation is a central component in allowing ST to play a key role in regulating nutrient utilization across a range of physiological situations. U.S. commercial use began in 1994, and adoption has been extensive. From a consumer perspective, bST was unique, and special interest groups loudly predicted dire consequences. However, introduction of bST had no impact on milk consumption, and milk labeled as recombinant bST-free occupies a minor niche market. From a producer perspective, commercial use verified scientific studies and enhanced net farm income. Overall, ST is a key homeorhetic control regulating nutrient partitioning, and the ST/IGF system plays a key role in animal performance and well being across a range of physiological situations.
            • Record: found
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            The nutrition of goat

            (1998)
              • Record: found
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              The pattern and manipulation of ovarian follicular growth in goats

              The understanding of the dynamics and regulation of follicle development in the goat has increased in recent years due to the use of ultrasonography. Previous findings observed in other ruminants extend to this species such as: the wavelike pattern of follicular growth with waves emerging every 5-7 days; the presence of follicular dominance, particularly during wave 1 and the ovulatory wave; and the role of progesterone concentrations on follicular wave turnover. However, traditional hormone treatments for oestrus synchronisation and superovulatory programs remain essentially unmodified and without taking into account this new information. The use of long progestogen priming is largely unjustified. Short progestogen priming can be used successfully in both anoestrous and cycling goats (in this case associated with PGF2alpha), and also linked with timed artificial insemination. On the other hand, recent attempts to overcome the deleterious effect of the dominant follicle on superovulatory response using the emergence of the wave 1 have been successful. Overall, using ultrasonography a new field has been opened and surely successful output will be forthcoming in the next years to improve reproductive management of the goat, the fastest growing ruminant population in the world.

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
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                Journal
                abmvz
                Arquivo Brasileiro de Medicina Veterinária e Zootecnia
                Arq. Bras. Med. Vet. Zootec.
                Universidade Federal de Minas Gerais, Escola de Veterinária (Belo Horizonte )
                1678-4162
                December 2007
                : 59
                : 6
                : 1500-1508
                Affiliations
                [1 ] Universidade Federal de Viçosa Brazil
                [2 ] Embrapa Caprinos e Ovinos Brazil
                [3 ] Embrapa Gado de Leite Brazil
                [4 ] Universidade Federal de Lavras Brazil
                Article
                S0102-09352007000600024
                10.1590/S0102-09352007000600024
                78ad65d2-d60f-4a65-b302-de5ba03ba6c2

                http://creativecommons.org/licenses/by/4.0/

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                SciELO Brazil

                Self URI (journal page): http://www.scielo.br/scielo.php?script=sci_serial&pid=0102-0935&lng=en
                Categories
                VETERINARY SCIENCES

                General veterinary medicine
                goats,follicular growth,dominant follicle,follicular waves,progesterone,caprino,crescimento folicular,folículo dominante,onda folicular,progesterona

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