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      The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.

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          Abstract

          Evidence-based guidelines for the management of patients with Lyme disease, human granulocytic anaplasmosis (formerly known as human granulocytic ehrlichiosis), and babesiosis were prepared by an expert panel of the Infectious Diseases Society of America. These updated guidelines replace the previous treatment guidelines published in 2000 (Clin Infect Dis 2000; 31[Suppl 1]:1-14). The guidelines are intended for use by health care providers who care for patients who either have these infections or may be at risk for them. For each of these Ixodes tickborne infections, information is provided about prevention, epidemiology, clinical manifestations, diagnosis, and treatment. Tables list the doses and durations of antimicrobial therapy recommended for treatment and prevention of Lyme disease and provide a partial list of therapies to be avoided. A definition of post-Lyme disease syndrome is proposed.

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          Most cited references 312

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          The optimism of the early period of antimicrobial discovery has been tempered by the emergence of bacterial strains with resistance to these therapeutics. Today, clinically important bacteria are characterized not only by single drug resistance but also by multiple antibiotic resistance--the legacy of past decades of antimicrobial use and misuse. Drug resistance presents an ever-increasing global public health threat that involves all major microbial pathogens and antimicrobial drugs.
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            The prevalence and characteristics of fibromyalgia in the general population

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                Author and article information

                Affiliations
                [1 ] Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA. Gary_Wormser@nymc.edu
                Journal
                Clin. Infect. Dis.
                Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
                1537-6591
                1058-4838
                Nov 1 2006
                : 43
                : 9
                CID40897 10.1086/508667 17029130

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