The upper extremity moves in coordinated motions to accomplish complex tasks.
1,2
This requires contraction of multiple muscles in unison for actions to occur in a
natural, seamless fashion.
2
For example, as one brings one's hand to his or her mouth, the shoulder externally
rotates, extends and adducts, while the hand supinates and the elbow flexes. The muscles
required to perform this movement are innervated by various terminal nerve branches
(eg, suprascapular, axillary, lateral pectoral nerve, musculocutaneous, radial nerve),
but fibers all originate from the same C5-6 nerve roots. Less natural motions require
more intentional action of the thorax, shoulder, and elbow. The purpose of this article
is to examine the organization of the brachial plexus in one simple, unifying theme:
muscles involved in synergistic function share a common nerve root, despite their
terminal branch.
The brachial plexus originates as 5 ventral roots from C5 to T1 and terminates as
5 motor branches that power the upper extremity. Between the roots and branches, the
plexus becomes 3 trunks, 6 divisions, and 3 cords. Along this course, the plexus gives
off 12 other terminal branches. The intervening convolution between the roots and
branches, at first glance, would seem unnecessary. The crossing divisions and contributions
from each cord provide complexity in anatomy that cannot be explained by redundancy,
as loss of a single nerve can lead to devastating loss of function.
The anatomical intricacies, however, can be explained as a highway system for nerve
roots to arrive at target muscles, with multiple muscles working together to perform
1 coordinated motion. The intervening trunks, divisions, and cords can be thought
of as simply a system to deliver axons from a similar nerve root to terminal branches
that reach the end target muscle of interest. Each of these motions occurs as a result
of various muscles contracting together and are all innervated by similar nerve roots,
despite variations in branches.
Cadaveric dissections demonstrate variations in innervation patterns. The triceps
receives nerve fibers from the radial nerve, axillary nerve, and/or even branches
off the ulnar nerve.
3,4
Anatomic discrepancies can also been seen for the extensor carpi radialis brevis between
the superficial branch of the radial nerve (55%), posterior interosseous nerve (2nd
most common), and radial nerve.
5
Despite the variability in terminal nerve branch, the derivative nerve root remains
consistent.
The more proximal and distal muscles are primarily innervated by the higher and lower
nerve roots, respectively. However, this is not uniformly true. For example, the pectoralis
major is the only muscle with 2 nerves directly off the brachial plexus and innervation
from every nerve root (lateral pectoral nerve C5, C6, C7 and medial pectoral nerve
C8, T1). The lack of innervation order can also be seen for the finger extensors.
The brachial plexus is a complex network of structure and function whose layout can
be simplified into axons going from point A (nerve root) to point B (synergistic muscle)
with the intervening trunks, cords and divisions being a system to deliver these axons
to synergistic muscles that co-contract in unison. As the philosophical principle,
Occam's razor, states, the simplest solution tends to be correct. This may very well
also be the case for the brachial plexus.