10
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Effect of salicylates on lymphocyte blastogenesis in vitro: association with other non-steroid anti-inflammatory drugs.

      Clinical Rheumatology
      Anti-Inflammatory Agents, pharmacology, Aspirin, Diflunisal, Humans, In Vitro Techniques, Indomethacin, Lymphocyte Activation, drug effects, Lymphocytes, Phytohemagglutinins, Prostaglandin Antagonists, Salicylates, Sodium Salicylate

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          High concentrations of the non-steroid anti-inflammatory drugs, alone and in association, reduce the blastogenesis of human lymphocytes in vitro. This effect is probably due to the toxicity of these agents and not to the inhibition of prostaglandin (PG) prosuction. Therefore drugs, such as, salicylates and associations of salicylates with other non-steroid anti-inflammatory drugs, which have a weak action on PG-synthesis, also inhibit proliferation of lymphocytes.

          Related collections

          Author and article information

          Comments

          Comment on this article