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      Pearls and Pitfalls of Optical Coherence Tomography Angiography Imaging: A Review

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          Abstract

          Optical coherence tomography angiography (OCTA) has significantly expanded our knowledge of the ocular vasculature. Furthermore, this imaging modality has been widely adopted to investigate different ocular and systemic diseases. In this review, a discussion of the fundamental principles of OCTA is followed by the application of this imaging modality to study the retinal and choroidal vessels. A proper comprehension of this imaging modality is essential for the interpretation of OCTA imaging applications in retinal and choroidal disorders.

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          Most cited references19

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          IN VIVO CHARACTERIZATION OF RETINAL VASCULARIZATION MORPHOLOGY USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

          To evaluate retinal vessel morphology using split-spectrum amplitude-decorrelation angiography with optical coherence tomography in healthy eyes.
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            Quantitative Analysis of Three Distinct Retinal Capillary Plexuses in Healthy Eyes Using Optical Coherence Tomography Angiography.

            To identify and quantify the three distinct retinal capillary plexuses and the foveal avascular zone (FAZ) in healthy subjects according to age using optical coherence tomography angiography (OCTA) with novel projection artifact removal (PAR) software and improved segmentation.
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              Quantitative morphometry of perifoveal capillary networks in the human retina.

              To quantify the distribution and morphometric characteristics of capillary networks in the human perifovea. To determine correlations between the location of neuronal subcellular compartments and the morphometric features of regional capillary networks in the layered retina.
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                Author and article information

                Contributors
                giuseppe.querques@hotmail.it
                Journal
                Ophthalmol Ther
                Ophthalmol Ther
                Ophthalmology and Therapy
                Springer Healthcare (Cheshire )
                2193-8245
                2193-6528
                13 March 2019
                13 March 2019
                June 2019
                : 8
                : 2
                : 215-226
                Affiliations
                [1 ]ISNI 0000000417581884, GRID grid.18887.3e, Ophthalmology Department, , San Raffaele University Hospital, ; Milan, Italy
                [2 ]ISNI 0000 0000 9632 6718, GRID grid.19006.3e, Department of Ophthalmology, , David Geffen School of Medicine at UCLA, ; Los Angeles, CA USA
                [3 ]ISNI 0000 0001 0097 5623, GRID grid.280881.b, Doheny Eye Institute, ; Los Angeles, CA USA
                [4 ]ISNI 0000 0004 0372 2033, GRID grid.258799.8, Department of Ophthalmology and Visual Sciences, , Kyoto University Graduate School of Medicine, ; Kyoto, Japan
                Article
                178
                10.1007/s40123-019-0178-6
                6513942
                30868418
                79639644-452a-48bb-8cad-263debc41870
                © The Author(s) 2019
                History
                : 14 January 2019
                Categories
                Review
                Custom metadata
                © The Author(s) 2019

                choriocapillaris,choroid,image analysis,optical coherence tomography angiography,retinal vessels

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