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      Resection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients.

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          Abstract

          Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line.

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          Author and article information

          Journal
          Eur. J. Cancer
          European journal of cancer (Oxford, England : 1990)
          Elsevier BV
          1879-0852
          0959-8049
          Jun 2017
          : 78
          Affiliations
          [1 ] Hepatobiliary Center, AP-HP Hôpital Paul Brousse, Université Paris-Sud, Inserm U935, Villejuif, France. Electronic address: rene.adam@aphp.fr.
          [2 ] Hepatobiliary Center, AP-HP Hôpital Paul Brousse, Université Paris-Sud, Inserm U935, Villejuif, France; Eastern Hepatobiliary Surgery Hospital/National Liver Cancer Center, Second Military Medical University, Shanghai, China.
          [3 ] Department of Oncology, AP-HP Hôpital Paul Brousse, Université Paris-Sud, Inserm U935, Villejuif, France.
          [4 ] Department of HPB Surgery and Transplantation, Curry Cabral Hospital, Lisbon, Portugal.
          [5 ] Department of Digestive Surgery, Hôpital Saint André, Bordeaux, France.
          [6 ] Hepatobiliary Surgery Unit, Agostino Gemelli Hospital, Catholic University of the Sacred Heart, Rome, Italy.
          [7 ] Department of HPB and Digestive Surgery, Ospedale Mauriziano Umberto I, Turin, Italy.
          [8 ] HPB Surgery and Transplantation Unit, Hôpital Saint-Luc, Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
          [9 ] Department of Oncology and Digestive Surgery, CHU Amiens-Picardie, Amiens, France.
          [10 ] Hepatobiliary and Pancreatic Surgery Unit, Department of Surgery, Dr. Josep Trueta Hospital, IdlBGi, Girona, Spain.
          [11 ] Department of Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland.
          [12 ] Unit of HPB Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
          [13 ] Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
          [14 ] Department of Surgery, Medical University of Vienna, General Hospital, Vienna, Austria.
          [15 ] Department of Oncologic Surgery, Institut Gustave Roussy, Villejuif, France.
          [16 ] Research Center of Surgery, Russian Academy of Medical Science, Moscow, Russia.
          [17 ] Division of Surgery A, Department of Surgery, GB Rossi Hospital, University of Verona, Verona, Italy.
          Article
          S0959-8049(17)30827-4
          10.1016/j.ejca.2017.03.009
          28407529
          797558fb-4146-47b6-b088-84624d2f332e
          History

          Colorectal cancer,Hepatectomy,Liver metastasis,Preoperative chemotherapy,Second line

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