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      Ultrastructure and function of cilia and spermatozoa flagella in a patient with Kartagener's syndrome.

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          Abstract

          A 37-year-old man with the characteristic clinical signs of Kartagener's syndrome, including bronchiectasia, chronic paranasal sinusitis, and situs inversus, was found to have immotile cilia and sperm. Electron microscopy demonstrated that the majority of cilia lacked dynein arms and radial spokes and that various defects of microorgans existed in the sperm. The most frequent defect was total defect of axoneme followed by defect of inner dynein arms in the sperm. These findings suggest an association between the structural abnormality of absent inner dynein arms and immotility of cilia and sperm in Kartagener's syndrome.

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          Author and article information

          Journal
          Intern. Med.
          Internal medicine (Tokyo, Japan)
          0918-2918
          0918-2918
          Jul 1993
          : 32
          : 7
          Affiliations
          [1 ] Department of Internal Medicine, Miyazaki Prefectural Hospital, Japan.
          Article
          8286842

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