Blog
About

6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      New perspectives in arsenic-induced cell signal transduction.

      Journal of Inorganic Biochemistry

      Apoptosis, drug effects, Arsenic, pharmacology, Arsenicals, Carcinogens, Cell Cycle, Humans, Mitogen-Activated Protein Kinase Kinases, metabolism, NF-kappa B, Reactive Oxygen Species, Signal Transduction

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Although the carcinogenicity of arsenic has been well established, the underlying molecular mechanisms have not yet been fully identified. Accumulating evidence indicates that the alteration of cellular signal transduction is directly related to the carcinogenesis of arsenic. This review focuses on recent advances in arsenic-induced signal transduction, including reactive oxygen species (ROS) production, tyrosine phosphorylation, MAPK signaling, NF-kappaB activation, cell cycle arrest, and apoptosis.

          Related collections

          Author and article information

          Journal
          12888263

          Comments

          Comment on this article