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Class of antiretroviral drugs and the risk of myocardial infarction.
Nina Friis-Møller ,
Peter Reiss ,
Caroline A Sabin ,
Rainer Weber ,
Antonella d'Arminio Monforte ,
Wafaa El-Sadr ,
Rodolphe Thiébaut ,
Stephane De Wit ,
Ole Kirk ,
Eric Fontas ,
Matthew G Law ,
Andrew Phillips ,
Jens D Lundgren
Apr 26 2007
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Abstract
We have previously demonstrated an association between combination antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this association differs according to the class of antiretroviral drugs. We conducted a study to investigate the association of cumulative exposure to protease inhibitors and nonnucleoside reverse-transcriptase inhibitors with the risk of myocardial infarction.