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      Neighbor-net: an agglomerative method for the construction of phylogenetic networks.

      1 ,
      Molecular biology and evolution
      Oxford University Press (OUP)

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          Abstract

          We present Neighbor-Net, a distance based method for constructing phylogenetic networks that is based on the Neighbor-Joining (NJ) algorithm of Saitou and Nei. Neighbor-Net provides a snapshot of the data that can guide more detailed analysis. Unlike split decomposition, Neighbor-Net scales well and can quickly produce detailed and informative networks for several hundred taxa. We illustrate the method by reanalyzing three published data sets: a collection of 110 highly recombinant Salmonella multi-locus sequence typing sequences, the 135 "African Eve" human mitochondrial sequences published by Vigilant et al., and a collection of 12 Archeal chaperonin sequences demonstrating strong evidence for gene conversion. Neighbor-Net is available as part of the SplitsTree4 software package.

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          Author and article information

          Journal
          Mol Biol Evol
          Molecular biology and evolution
          Oxford University Press (OUP)
          0737-4038
          0737-4038
          Feb 2004
          : 21
          : 2
          Affiliations
          [1 ] McGill Centre for Bioinformatics, Montreal, Quebec, Canada. bryant@mcb.mcgill.ca
          Article
          msh018
          10.1093/molbev/msh018
          14660700
          7a845fe5-6510-4dfa-9ee6-d411c4438796

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