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      Infection of central nervous system by motile Enterococcus: first case report.

      Journal of Clinical Microbiology
      Aged, Central Nervous System Bacterial Infections, diagnosis, drug therapy, Drug Therapy, Combination, therapeutic use, Enterococcus, classification, isolation & purification, physiology, Fever, Gentamicins, Gram-Positive Bacterial Infections, Humans, Hydrocephalus, etiology, surgery, Male, Meningitis, complications, Microbial Sensitivity Tests, Recurrence, Vancomycin, Ventriculoperitoneal Shunt, adverse effects

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          Abstract

          A 66-year-old man with four indwelling ventriculoperitoneal shunts for multiloculated hydrocephalus from a complicated case of meningitis a year before developed shunt infection based on a syndrome of fever, drowsiness, and cerebrospinal fluid neutrophil pleocytosis in the background of repeated surgical manipulation to relieve successive shunt blockages. The cerebrospinal fluid culture, which yielded a motile Enterococcus species, was believed to originate from the gut. This isolate was lost in storage and could not be characterized further. The patient improved with vancomycin and high-dose ampicillin therapy. He relapsed a month later with Enterococcus gallinarum shunt infection, which responded to high-dose ampicillin and gentamicin therapy. This is probably the first case report of motile Enterococcus infection of the central nervous system.

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