+1 Recommend
0 collections
      • Record: found
      • Abstract: found
      • Article: not found

      Toxicity of chemotherapy and radiation on female reproduction.

      Clinical obstetrics and gynecology
      Antineoplastic Agents, adverse effects, Apoptosis, Atrophy, etiology, Female, Fertility, Humans, Infertility, Female, Maternal Age, Neoplasms, drug therapy, radiotherapy, Ovarian Follicle, pathology, Ovary, drug effects, radiation effects, Primary Ovarian Insufficiency, Radiotherapy, Uterus

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          One of the most devastating consequences of cancer treatment in the young female population is ovarian damage, resulting in diminished fertility potential. The extent of damage is related to age, chemotherapeutic regimen, and dose of pelvic radiation received. It is crucial that physicians know the impact each of these factors has on future fertility to advice patients on fertility preservation options. Anticancer drugs injure the female reproductive system through ovarian follicular and stromal damage. Although the exact mechanisms of damage remain unclear, it is essential to better understand these mechanisms to develop methods to diminish ovarian injury.

          Related collections

          Author and article information


          Comment on this article