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      Is Open Access

      Do ancient types of wheat have health benefits compared with modern bread wheat?

      review-article
      Journal of Cereal Science
      Academic Press
      Ancient wheat, Health benefits, Allergy, Intolerance

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          Abstract

          A number of studies have suggested that ancient wheats have health benefits compared with modern bread wheat. However, the mechanisms are unclear and limited numbers of genotypes have been studied, with a particular focus on Kamut ® (Khorasan wheat). This is important because published analyses have shown wide variation in composition between genotypes, with further effects of growth conditions. The present article therefore critically reviews published comparisons of the health benefits of ancient and modern wheats, in relation to the selection and growth of the lines, including dietary interventions and comparisons of adverse effects (allergy, intolerance, sensitivity). It is concluded that further studies are urgently required, particularly from a wider range of research groups, but also on a wider range of genotypes of ancient and modern wheat species. Furthermore, although most published studies have made efforts to ensure the comparability of material in terms of growth conditions and processing, it is essential that these are standardised in future studies and this should perhaps be a condition of publication.

          Highlights

          • Critically appraises the health benefits of ancient wheats in relationship to grain composition.

          • Includes human intervention trials and in vitro studies.

          • Included metabolic and adverse effects.

          • Makes recommendations for future work.

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          Most cited references61

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          Genome plasticity a key factor in the success of polyploid wheat under domestication.

          Wheat was domesticated about 10,000 years ago and has since spread worldwide to become one of the major crops. Its adaptability to diverse environments and end uses is surprising given the diversity bottlenecks expected from recent domestication and polyploid speciation events. Wheat compensates for these bottlenecks by capturing part of the genetic diversity of its progenitors and by generating new diversity at a relatively fast pace. Frequent gene deletions and disruptions generated by a fast replacement rate of repetitive sequences are buffered by the polyploid nature of wheat, resulting in subtle dosage effects on which selection can operate.
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            The prevalence of plant food allergies: a systematic review.

            There is uncertainty regarding the prevalence of allergies to plant food. To assess the prevalence of allergies to plant food according to the different subjective and objective assessment methods. Our systematic search of population-based studies (since 1990) in the literature database MEDLINE focused on fruits, vegetables/legumes, tree nuts, wheat, soy, cereals, and seeds. Prevalence estimates were categorized by food item and method used (food challenges, skin prick test, serum IgE, parent/self-reported symptoms), complemented by appropriate meta-analyses. We included 36 studies with data from a total of over 250,000 children and adults. Only 6 studies included food challenge tests with prevalences ranging from 0.1% to 4.3% each for fruits and tree nuts, 0.1% to 1.4% for vegetables, and < 1% each for wheat, soy, and sesame. The prevalence of sensitization against any specific plant food item assessed by skin prick test was usually < 1%, whereas sensitization assessed by IgE against wheat ranged as high as 3.6% and against soy as high as 2.9%. For fruit and vegetables, prevalences based on perception were generally higher than those based on sensitization, but for wheat and soy in adults, sensitization was higher. Meta-analyses showed significant heterogeneity between studies regardless of food item or age group. Population-based prevalence estimates for allergies to plant products determined by the diagnostic gold standard are scarce. There was considerable heterogeneity in the prevalence estimates of sensitization or perceived allergic reactions to plant food.
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              Improving the protein content and composition of cereal grain

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                Author and article information

                Contributors
                Journal
                J Cereal Sci
                J. Cereal Sci
                Journal of Cereal Science
                Academic Press
                0733-5210
                1 January 2018
                January 2018
                : 79
                : 469-476
                Affiliations
                [1]Department of Plant Science, Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, UK
                [2]School of Agriculture, Policy and Development, University of Reading, Earley Gate, Reading RG6 6AR, UK
                Author notes
                []Department of Plant Science, Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, UK.Department of Plant ScienceRothamsted ResearchHarpendenHertfordshireAL5 2JQUK peter.shewry@ 123456rothamsted.ac.uk
                Article
                S0733-5210(17)30826-3
                10.1016/j.jcs.2017.11.010
                5824670
                29497244
                7aed731d-9e8e-46d1-84a9-54deaf1974d3
                © 2017 The Author

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 12 October 2017
                : 18 November 2017
                Categories
                Article

                ancient wheat,health benefits,allergy,intolerance
                ancient wheat, health benefits, allergy, intolerance

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