Blog
About

81
views
0
recommends
+1 Recommend
1 collections
    3
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Metabolomics and its application in the treatment of coronary heart disease with traditional Chinese medicine

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Traditional Chinese Medicine (TCM) is the treasure of Chinese Nation and gained the gradual acceptance of the international community. However, the methods and theories of TCM understanding of diseases are lack of appropriate modern scientific characterization systems. Moreover, traditional risk factors cannot promote to detection and prevent those patients with coronary artery disease (CAD) who have not developed acute myocardial infarction (MI) in time. To sum up, there is still no objective systematic evaluation system for the therapeutic mechanism of TCM in the prevention and cure of cardiovascular disease. Thus, new ideas and technologies are needed. The development of omics technology, especially metabolomics, can be used to predict the level of metabolites in vivo and diagnose the physiological state of the body in time to guide the corresponding intervention. In particular, metabolomics is also a very powerful tool to promote the modernization of TCM and the development of TCM in personalized medicine. This article summarized the application of metabolomics in the early diagnosis, the discovery of biomarkers and the treatment of TCM in CAD.

          Related collections

          Author and article information

          Journal
          CJNM
          Chinese Journal of Natural Medicines
          Elsevier
          1875-5364
          20 May 2019
          : 17
          : 5
          : 321-330
          Affiliations
          1 Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
          2 School of Pharmacy, Second Military Medical University, Shanghai 200433, China
          Author notes
          *Corresponding author: LI Hou-Kai, Tel: 86-21-51322729, Fax: 86-2151322729, E-mails: houkai1976@ 123456126.com ; ZHANG Wei-Dong, wdzhangy@ 123456hotmail.com

          These authors have no conflict of interest to declare.

          Article
          S1875-5364(19)30037-8
          10.1016/S1875-5364(19)30037-8
          31171266
          Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.
          Funding
          Funded by: Professor of Chang Jiang Scholars Program, NSFC
          Award ID: 81520108030
          Award ID: 21472238
          Award ID: 81873059
          Award ID: 81673662
          Funded by: Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products
          Award ID: 16DZ2280200
          Funded by: Scientific Foundation of Shanghai, China
          Award ID: 13401900103
          Award ID: 13401900101
          Funded by: National Key Research and Development Pro-gram of China
          Award ID: 2017YFC1700200
          This work was supported by Professor of Chang Jiang Scholars Program, NSFC (Nos. 81520108030, 21472238, 81873059 and 81673662), Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (No. 16DZ2280200), the Scientific Foundation of Shanghai, China (Nos. 13401900103 and 13401900101), the National Key Research and Development Pro-gram of China (No. 2017YFC1700200) and Shuguang Scholar (16SG36) at Shanghai Institutions of Higher Learning from Shanghai Municipal Education Commission.
          Categories
          Reviews

          Comments

          Comment on this article