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      Left ventricular hypertrophy and hypertension

      , , , , ,
      Progress in Cardiovascular Diseases
      Elsevier BV

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          Abstract

          Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage. In addition to being a marker of HTN, LV geometrical changes: concentric remodeling, concentric or eccentric LV hypertrophy (LVH) are major independent risk factors for not only CVD morbidity and mortality but also for all-cause mortality and neurological pathologies. Blood pressure control with lifestyle changes and antihypertensive agents has been demonstrated to prevent and regress LVH. Herein, we provide a comprehensive review of literature on the relationship between HTN and LV geometry abnormalities with a focus on diagnosis, prognosis, pathophysiological mechanisms, and treatment approaches.

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          Author and article information

          Journal
          Progress in Cardiovascular Diseases
          Progress in Cardiovascular Diseases
          Elsevier BV
          00330620
          November 2019
          November 2019
          Article
          10.1016/j.pcad.2019.11.009
          31759953
          7b095431-0cd4-46e9-9403-d32b3daa2533
          © 2019

          https://www.elsevier.com/tdm/userlicense/1.0/

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