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Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections.
Emil Lesho
1 ,
Eun-Jeong Yoon ,
Patrick McGann ,
Erik Snesrud ,
Yoon Kwak ,
Michael Milillo ,
Fatma Onmus-Leone ,
Lan Preston ,
Kristina St Clair ,
Mikeljon Nikolich ,
Helen Viscount ,
Glenn Wortmann ,
Michael Zapor ,
Catherine Grillot-Courvalin ,
Patrice Courvalin ,
Robert Clifford ,
Paige E Waterman
Oct 01 2013
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Abstract
Colistin resistance is of concern since it is increasingly needed to treat infections caused by bacteria resistant to all other antibiotics and has been associated with poorer outcomes. Longitudinal data from in vivo series are sparse.