0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Pemphigoid diseases: pathogenesis, diagnosis, and treatment.

      Autoimmunity
      Humans, Skin Diseases, Vesiculobullous, diagnosis, etiology, therapy

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Pemphigoid diseases (including bullous pemphigoid, mucous membrane pemphigoid, pemphigoid gestationis, linear IgA dermatosis, lichen planus pemphigoides, and anti-p200 pemphigoid) are a subgroup of autoimmune bullous skin diseases characterized by an autoantibody response toward structural components of the hemidesmosome resulting in subepidermal blistering. By the use of different in vitro systems and experimental animal models, the pathogenic relevance of these autoantibodies has been demonstrated. Recent advances in the understanding of autoantibody responses have led to novel diagnostic tools and a more differentiated therapeutic approach for these disorders. This review covers the most recent understanding of the pathophysiology, diagnosis, and treatment of this group of autoimmune diseases.

          Related collections

          Author and article information

          Journal
          21923615
          10.3109/08916934.2011.606447

          Chemistry
          Humans,Skin Diseases, Vesiculobullous,diagnosis,etiology,therapy
          Chemistry
          Humans, Skin Diseases, Vesiculobullous, diagnosis, etiology, therapy

          Comments

          Comment on this article