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Genetic effects on treatment response of umeclidinium/vilanterol in chronic obstructive pulmonary disease
Lynn Condreay ,
Lingkang Huang ,
Elizabeth Harris ,
Jean Brooks ,
John H. Riley ,
Alison Church ,
Soumitra Ghosh
May 2016
May 2016
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Abstract
Treatment with long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists
(LAMAs) for chronic obstructive pulmonary disease (COPD) is standard, but response
varies. We investigated genetic association with treatment response to umeclidinium
(UMEC, a LAMA), vilanterol (VI, a LABA), and combination therapy.