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      The 24-h lung-function profile of once-daily tiotropium and olodaterol fixed-dose combination in chronic obstructive pulmonary disease.

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          Abstract

          This study investigated the effects on 24-h lung function and lung volume of a once-daily fixed-dose combination (FDC) of the long-acting muscarinic antagonist tiotropium and the long-acting β2-agonist olodaterol in patients with chronic obstructive pulmonary disease.

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          Author and article information

          Journal
          Pulm Pharmacol Ther
          Pulmonary pharmacology & therapeutics
          1522-9629
          1094-5539
          Jun 2015
          : 32
          Affiliations
          [1 ] Insaf GmbH Institut für Atemwegsforschung, Wiesbaden, Germany. Electronic address: k.beeh@insaf-wi.de.
          [2 ] Pulmonary and Sleep Associates of Jasper, Jasper, AL, USA.
          [3 ] Pulmonary Research Institute at LungClinic Grosshansdorf GmbH, Airway Research Center North, Grosshansdorf, Germany.
          [4 ] Centre de Recherche Appliquée en Allergie de Québec, Québec, Canada.
          [5 ] Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany.
          [6 ] Boehringer Ingelheim, Burlington, Ontario, Canada.
          [7 ] Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany; Department of Sports Medicine, Medical Clinic V, University of Tübingen, Tübingen, Germany.
          [8 ] Ghent University Hospital, Ghent, Belgium.
          Article
          S1094-5539(15)00044-9
          10.1016/j.pupt.2015.04.002
          25956072
          7bcbae39-c9ce-46e2-9fa3-1d0dd00fba0e
          Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
          History

          Chronic obstructive pulmonary disease,Combination therapy,Olodaterol,Tiotropium

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