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      • Record: found
      • Abstract: found
      • Article: found

      Electroretinographic Response in WAG/Rij Rats after Low-Intensity Cyclic Light Exposure

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          Abstract

          In order to investigate the combined influence of age and light, the b-wave and oscillatory potentials (OPs) of the electroretinogram (ERG) were recorded in 1.5-, 7- and 12-month-old WAG/Rij rats, reared under homogenous low-intensity cyclic light exposure. Wistar albino rats of the same ages, reared under the same conditions, served as controls. The b-wave amplitude decreased, and its implicit time increased in the older age groups significantly more in WAG/Rij than in Wistar rats. Statistical analysis indicated that the b-wave amplitude is a more suitable parameter than implicit time in differentiating the ERG variations of one rat strain from the other. The added amplitude of the OPs also decreased in older age groups, but differently from the b wave. This occurred in WAG/Rij rats already at 1.5 months of age.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1993
          Publication date (Print): 1993
          Publication date (Electronic): 11 December 2009
          Volume: 25
          Issue: 3
          Pages: 137-144
          Affiliations
          aUniversity Eye Clinic, bInstitute of Experimental Medicine of the National Research Council, and cInstitute of Neuropsychiatry, University of Palermo, Italy
          Article
          Publisher ID: 267282 Other ID: Ophthalmic Res 1993;25:137–144
          DOI: 10.1159/000267282
          PubMed ID: 8336900
          SO-VID: 7c2c3d27-657e-4c10-b796-907c849730ef
          Copyright © © 1993 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 21 December 1990
          Date accepted : 04 December 1992
          Page count
          Pages: 8
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: WAG/Rij rats,Electroretinogram,Wistar rats,Low-intensity cyclic light exposure
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: WAG/Rij rats, Electroretinogram, Wistar rats, Low-intensity cyclic light exposure

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