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      Pregnancy after 24 Postoperative Months of Roux-En-Y Gastric Bypass Presents Risk of Pregnancy Complications Similar to Pregnancy within the First Postoperative Year

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          Abstract

          Background: To assess the influence of the time interval between pregnancy and the Roux-en-Y gastric bypass (RYGB) on maternal-infant complications. Methods: This is an analytical, longitudinal and retrospective study comprising 42 pregnant women who had previously undergone RYGB, subdivided according to the time interval between pregnancy and bariatric surgery: ≤12 months (G1), >12 and <24 months (G2) and ≥24 months (G3). Anthropometric variables of mothers, newborns and information on pregnancy complications were collected. Results: G1 was the group more likely to develop urinary tract infection, dumping syndrome and inadequacy of birth weight than G2. Pregnancy complications were similar and >80.0% both in the first 12 months and after 24 months of the RYGB and the smallest percentages occurred in the time interval of 12–24 months after it. In addition, the percentage of neonatal complications was the highest in G1 when compared to the other times studied. Conclusion: Our findings indicate less predisposition to maternal-infant complications in pregnancies occurring in the time interval of >12 and <24 months and suggest that pregnancy after 24 months can be as harmful as pregnancies occurring before the first 12 postoperative months, since a great catabolism occurs at this time as it has been shown in the literature.

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          Author and article information

          Journal
          ANM
          Ann Nutr Metab
          10.1159/issn.0250-6807
          Annals of Nutrition and Metabolism
          S. Karger AG
          0250-6807
          1421-9697
          2019
          September 2019
          09 July 2019
          : 75
          : 1
          : 24-30
          Affiliations
          [_a] aDoctor of Science from the School of Medicine at the Federal University of Rio de Janeiro, Researcher of the NPqM at the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
          [_b] bDoctor of Science from the School of Medicine at the Federal University of Rio de Janeiro, Professor of the Federal Fluminense University, Researcher of the NPqM at the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
          [_c] cMaster of Science Student at the School of Medicine at the Federal University of Rio de Janeiro, Researcher of the NPqM at the Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
          [_d] dDoctor in Science from the School of Medicine of the Federal University of Rio de Janeiro, Multidisciplinary Center for Bariatric and Metabolic Surgery, Researcher of the Center for Research on Micronutrients (NPqM) of the Institute of Nutrition Josué de Castro of UFRJ, Rio de Janeiro, Brazil
          [_e] eDoctor of Science from the Federal University of São Paulo (UNIFESP), Member of the Brazilian Society of Bariatric and Metabolic Surgery, Multidisciplinary Center for Bariatric and Metabolic Surgery, Member of the Center for Research on Micronutrients (NPqM) of the Institute of Nutrition Josué de Castro of UFRJ, Rio de Janeiro, Brazil
          [_f] fDoctor of Science from ENSP/FIOCRUZ, Full Professor of the Department of Social and Applied Nutrition of the Institute of Nutrition at UFRJ, Coordinator of the Center for Research on Micronutrients (NPqM) of the Institute of Nutrition Josué de Castro of UFRJ, Rio de Janeiro, Brazil
          Author notes
          *Sabrina Cruz, Doctor of Science from the School of Medicine at the Federal University of Rio de Janeiro, Researcher of the NPqM at the Federal University of Rio de Janeiro, Av.Carlos Chagas, No. 373, Edifício do Centro de Ciências da Saúde, 2 andar, Sala 49 Cidade Universitária, Ilha do Fundão, Rio de Janeiro 21.941-902 (Brasil), E-Mail sabrina.cruz.ufrj@gmail.com
          Article
          501423 Ann Nutr Metab 2019;75:24–30
          10.1159/000501423
          31288227
          7c316ce0-ce70-42da-8091-131af92a8cd2
          © 2019 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 04 April 2019
          : 09 June 2019
          Page count
          Figures: 1, Tables: 2, Pages: 7
          Categories
          Clinical Study: Research Article

          Nutrition & Dietetics,Health & Social care,Public health
          Pregnancy complications,Pregnancy,Roux-en-Y gastric bypass,Bariatric surgery,Time-to-conception,Neonatal complications

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