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Effectiveness of antiretroviral treatment in a South African program: a cohort study.
Lara R Fairall
1 ,
Max O Bachmann ,
Goedele M C Louwagie ,
Cloete van Vuuren ,
Perpetual Chikobvu ,
Dewald Steyn ,
Gillian H Staniland ,
Venessa Timmerman ,
Mpumelelo Msimanga ,
Chris J Seebregts ,
Andrew Boulle ,
Ralph Nhiwatiwa ,
Eric D Bateman ,
Merrick F Zwarenstein ,
Ronald D Chapman
Jan 14 2008
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Abstract
The effectiveness of the South African government's expanding antiretroviral treatment program is unknown. Observational studies of treatment effectiveness are prone to selection bias, rarely compare patients receiving antiretroviral treatment with similar patients not receiving antiretroviral treatment, and underestimate mortality rates unless patients are actively followed up.