4
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Advances in the molecular genetics of gliomas — implications for classification and therapy

      , , ,

      Nature Reviews Clinical Oncology

      Springer Nature

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          In 2016, a revised WHO classification of glioma was published, in which molecular data and traditional histological information are incorporated into integrated diagnoses. Herein, the authors highlight the developments in our understanding of the molecular genetics of gliomas that underlie this classification, and review the current landscape of molecular biomarkers used in the classification of disease subtypes. In addition, they discuss how these advances can promote the development of novel pathogenesis-based therapeutic approaches, paving the way to precision medicine.

          Related collections

          Author and article information

          Journal
          Nature Reviews Clinical Oncology
          Nat Rev Clin Oncol
          Springer Nature
          1759-4774
          1759-4782
          December 29 2016
          December 29 2016
          :
          :
          Article
          10.1038/nrclinonc.2016.204
          28031556
          7c902669-4db1-4956-9ae0-d68b9440aa78
          © 2016

          Comments

          Comment on this article