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      Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group.

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          Abstract

          Sildenafil is a potent inhibitor of cyclic guanosine monophosphate hydrolysis [corrected] in the corpus cavernosum and therefore increases the penile response to sexual stimulation. We evaluated the efficacy and safety of sildenafil, administered as needed in two sequential double-blind studies of men with erectile dysfunction of organic, psychogenic, and mixed causes.

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          Author and article information

          Journal
          N Engl J Med
          The New England journal of medicine
          Massachusetts Medical Society
          0028-4793
          0028-4793
          May 14 1998
          : 338
          : 20
          Affiliations
          [1 ] Department of Urology, Boston University Medical Center, MA 02118, USA.
          Article
          10.1056/NEJM199805143382001
          9580646
          7cafddca-ae7d-4d80-b14a-31bd7862a091
          History

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