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Lessons in the genomic diversity of malaria.

Author(s): M Ibrahim, A. Ranciaro, TB Nyambo, S. Bumpstead, G Lema, JB Hirbo, K. Powell, JS Silverman, GA Wray, SA Omar, HM Mortensen, SA Tishkoff, FA Reed, JK Pritchard, P Deloukas, BF Voight, CC Babbitt, J Ghori, M Osman

Publication date: 2006-12-31

Journal: Nature genetics

Keywords: Animals, Chromosome Mapping, Genetic Variation, Genome, Protozoan, Humans, Malaria, Falciparum, parasitology, Plasmodium falciparum, genetics

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Abstract

Genome-wide characterization of Plasmodium falciparum genetic diversity represents an important step in malaria genetics. The organizational and collaborative efforts to reach this goal and the results on linkage disequilibrium and genetic diversity among worldwide isolates provide general lessons.

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PubMed ID:: 17192776

DOI:: 10.1038/ng0107-1

ScienceOpen disciplines: Chemistry

Keywords: Animals,Chromosome Mapping,Genetic Variation,Genome, Protozoan,Humans,Malaria, Falciparum,parasitology,Plasmodium falciparum,genetics

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ScienceOpen disciplines: Chemistry

Keywords: Animals, Chromosome Mapping, Genetic Variation, Genome, Protozoan, Humans, Malaria, Falciparum, parasitology, Plasmodium falciparum, genetics

Lessons in the genomic diversity of malaria.

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Malaria vaccine development

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