Cardioverter defibrillator implantation without induction of ventricular fibrillation: a single-blind, non-inferiority, randomised controlled trial (SIMPLE).

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Abstract

Defibrillation testing by induction and termination of ventricular fibrillation is widely done at the time of implantation of implantable cardioverter defibrillators (ICDs). We aimed to compare the efficacy and safety of ICD implantation without defibrillation testing versus the standard of ICD implantation with defibrillation testing.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Feb 28 2015

Volume: 385

Issue: 9970

Affiliations

[1 ] Population Health Research Institute, McMaster University, Hamilton, ON, Canada. Electronic address: Jeff.Healey@phri.ca.

[2 ] JW Goethe University, Frankfurt, Germany.

[3 ] Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel.

[4 ] Klinikum Kassel, Kassel, Germany.

[5 ] Centre Hospitalier Universitaire, Rennes, France.

[6 ] Hospital de Santa Creu i Sant Pau, Barcelona, Spain.

[7 ] Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

[8 ] Institut Universitaire de Cardiologie et de Pneumologie de Québec, QC, Canada.

[9 ] Leiden University Medical Center, Leiden, the Netherlands.

[10 ] Karolinska Institute, Stockholm, Sweden.

[11 ] Population Health Research Institute, McMaster University, Hamilton, ON, Canada.

[12 ] Boston Scientific, Minneapolis MN, USA, and Brussels, Belgium.

[13 ] Semmelweis University, Heart and Vascular Centre, Budapest, Hungary.

[14 ] Gottsegen National Institute of Cardiology, Budapest, Hungary.

[15 ] Montreal Heart Institute, Montreal, QC, Canada.

Article

Publisher Item ID: S0140-6736(14)61903-6

DOI: 10.1016/S0140-6736(14)61903-6

PubMed ID: 25715991

SO-VID: 7ce5c3ce-11ed-4066-991e-fbb717522bbd

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