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      Covalent organic nanosheets for bioimaging†

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          Abstract

          Non-toxic covalent organic nanosheet-based fluorescent nuclear stains.

          Abstract

          Covalent organic nanosheets (CONs) have attracted much attention because of their excellent physical, chemical, electronic, and optical properties. Although covalent organic nanosheets have widely been used in many applications, there are only a few CONs that have been tested for bio-medical applications. Nanometer sized triazine-based nanosheets were obtained by exfoliating their bulk counterparts in water. The obtained nanosheets were dispersible and stable in water with enhanced photoluminescence properties compared to the bulk material. The nanosheets were biocompatible and non-toxic and showed ability to stain HeLa cell nuclei without additional assistance of an external targeting agent.

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          Author and article information

          Journal
          Chem Sci
          Chem Sci
          Chemical Science
          Royal Society of Chemistry
          2041-6520
          2041-6539
          3 September 2018
          28 November 2018
          : 9
          : 44
          : 8382-8387
          Affiliations
          [a ] Chemistry Program , New York University Abu Dhabi (NYUAD) , United Arab Emirates . Email: at105@ 123456nyu.edu
          [b ] Engineering Division , New York University Abu Dhabi (NYUAD) , United Arab Emirates
          [c ] The Materials Science Factory , Instituto de Ciencia de Materiales de Madrid - CSIC , Sor Juana Inés de la Cruz 3 , 28049 Madrid , Spain
          [d ] Photoactivated Processes Unit , IMDEA Energy , Avd. Juan de la Sagra 3 , Mostoles 28935, Madrid , Spain
          [e ] United Arab Emirates University , College of Science , Department of Chemistry , Al-Ain , United Arab Emirates
          [f ] School of Pharmaceutical Science and Technology , Health Science Platform , Tianjin University , 92 Weijin Rd. Nankai, District , Tianjin 300072 , P. R. China
          Author notes

          ‡These authors contributed equally to this work.

          Article
          c8sc02842g
          10.1039/c8sc02842g
          6243473
          This journal is © The Royal Society of Chemistry 2018

          This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)

          Categories
          Chemistry

          Notes

          †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02842g

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