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      ‘Liking’ and ‘wanting’ food rewards: Brain substrates and roles in eating disorders

      Physiology & Behavior

      Elsevier BV

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          Abstract

          What brain reward systems mediate motivational 'wanting' and hedonic 'liking' for food rewards? And what roles do those systems play in eating disorders? This article surveys recent findings regarding brain mechanisms of hedonic 'liking', such as the existence of cubic-millimeter hedonic hotspots in nucleus accumbens and ventral pallidum for opioid amplification of sensory pleasure. It also considers brain 'wanting' or incentive salience systems important to appetite, such as mesolimbic dopamine systems and opioid motivation circuits that extend beyond the hedonic hotspots. Finally, it considers some potential ways in which 'wanting' and 'liking' might relate to eating disorders.

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          Author and article information

          Journal
          Physiology & Behavior
          Physiology & Behavior
          Elsevier BV
          00319384
          July 2009
          July 2009
          : 97
          : 5
          : 537-550
          Article
          10.1016/j.physbeh.2009.02.044
          2717031
          19336238
          © 2009

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