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      Resuscitative endovascular balloon occlusion of the aorta (REBOA): a population based gap analysis of trauma patients in England and Wales

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          Abstract

          Introduction

          Non-compressible torso haemorrhage (NCTH) carries a high mortality in trauma as many patients exsanguinate prior to definitive haemorrhage control. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an adjunct that has the potential to bridge patients to definitive haemostasis. However, the proportion of trauma patients in whom REBOA may be utilised is unknown.

          Methods

          We conducted a population based analysis of 2012–2013 Trauma Audit and Research Network (TARN) data. We identified the number of patients in whom REBOA may have been utilised, defined by an Abbreviated Injury Scale score ≥3 to abdominal solid organs, abdominal or pelvic vasculature, pelvic fracture with ring disruption or proximal traumatic lower limb amputation, together with a systolic blood pressure <90 mm Hg. Patients with non-compressible haemorrhage in the mediastinum, axilla, face or neck were excluded.

          Results

          During 2012–2013, 72 677 adult trauma patients admitted to hospitals in England and Wales were identified. 397 patients had an indication(s) and no contraindications for REBOA with evidence of haemorrhagic shock: 69% men, median age 43 years and median Injury Severity Score 32. Overall mortality was 32%. Major trauma centres (MTCs) received the highest concentration of potential REBOA patients, and would be anticipated to receive a patient in whom REBOA may be utilised every 95 days, increasing to every 46 days in the 10 MTCs with the highest attendance of this injury type.

          Conclusions

          This TARN database analysis has identified a small group of severely injured, resource intensive patients with a highly lethal injury that is theoretically amenable to REBOA. The highest density of these patients is seen at MTCs, and as such a planned evaluation of REBOA should be further considered in these hospitals.

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          Most cited references24

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          Death on the battlefield (2001–2011)

          Journal of Trauma and Acute Care Surgery, 73, S431-S437
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            Preventable or potentially preventable mortality at a mature trauma center.

            The objective of this study was to analyze the preventable and potentially preventable deaths occurring at a mature Level I trauma center. All trauma patients that died during their initial hospital admission during an 8-year period (January, 1998 to December, 2005) were analyzed. The deaths were initially reviewed at a weekly Morbidity and Mortality (M&M) conference followed by a multidisciplinary (Trauma Surgery, Critical Care, Emergency Medicine, Neurosurgery, Nursing, and Coroner) Combined Trauma Death Review Committee, and were classified into nonpreventable, potentially preventable, and preventable deaths. All preventable and potentially preventable deaths were identified for the purpose of the study. Quality improvement death forms included data on epidemiology, vital signs, injury severity, type of injury, probability of survival with Trauma and Injury Severity Score methodology, preventability (nonpreventable, potentially preventable, and preventable deaths), errors in the evaluation and management of the patient, and classification of errors (system, judgment, knowledge). Additional injury details, clinical course, circumstances leading to the death and autopsy findings were abstracted from the trauma registry and individual chart review. During the study period, 35,311 patients meeting trauma registry criteria were admitted and a total of 2,081 (5.9%) deaths occurred. Fifty-one deaths were classified as preventable or potentially preventable deaths (0.1% of admissions, 2.5% of deaths). Eleven of them (0.53% of deaths) were classified as preventable and 40 (1.92% of deaths) as potentially preventable deaths. Mean age was 40 years, 66.7% were men, mean Injury Severity Score was 27, 74.5% were blunt. The most common cause of death was bleeding (20, 39.2%) followed by multiple organ dysfunction syndrome (14, 27.5%) and cardiorespiratory arrest (8, 15.6%). This was caused by a delay in treatment (27, 52.9%), clinical judgment error (11, 21.6%), missed diagnosis (6, 11.8%), technical error (4, 7.8%), and other (3, 5.9%). The deaths peaked at two time periods: 26 (51.1%) during the first 24 hours and 16 (31.4%) after 7 days. Only one patient (2.0%) died in the first hour. The most common location of death was the intensive care unit (28, 54.9%), operating room (13, 25.5%), and emergency room (5, 9.8%). Preventable or potentially preventable deaths are rare but do occur at an academic Level I trauma center. Delay in treatment and error in judgment are the leading causes of preventable and potentially preventable deaths.
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              A clinical series of resuscitative endovascular balloon occlusion of the aorta for hemorrhage control and resuscitation.

              A requirement for improved methods of hemorrhage control and resuscitation along with the translation of endovascular specialty skills has resulted in reappraisal of resuscitative endovascular balloon occlusion of the aorta (REBOA) for end-stage shock. The objective of this report was to describe implementation of REBOA in civilian trauma centers. Descriptive case series of REBOA (December 2012 to March 2013) used in scenarios of end-stage hemorrhagic shock at the University of Maryland, R. Adams Cowley Shock Trauma Center, Baltimore, Maryland, and Herman Memorial Hospital, The Texas Trauma Institute, Houston, Texas. REBOA was performed by trauma and acute care surgeons for blunt (n = 4) and penetrating (n = 2) mechanisms. Three cases were REBOA in the descending thoracic aorta (Zone I) and three in the infrarenal aorta (Zone III). Mean (SD) systolic blood pressure at the time of REBOA was 59 (27) mm Hg, and mean (SD) base deficit was 13 (5). Arterial access was accomplished using both direct cutdown (n = 3) and percutaneous (n = 3) access to the common femoral artery. REBOA resulted in a mean (SD) increase in blood pressure of 55 (20) mm Hg, and the mean (SD) aortic occlusion time was 18 (34) minutes. There were no REBOA-related complications, and there was no hemorrhage-related mortality. REBOA is a feasible and effective means of proactive aortic control for patients in end-stage shock from blunt and penetrating mechanisms. With available technology, this method of resuscitation can be performed by trauma and acute care surgeons who have benefited from instruction on a limited endovascular skill set. Future work should be aimed at devices that allow easy, fluoroscopy-free access and studies to define patients most likely to benefit from this procedure. Therapeutic study, level V.
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                Author and article information

                Journal
                Emerg Med J
                Emerg Med J
                emermed
                emj
                Emergency Medicine Journal : EMJ
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                1472-0205
                1472-0213
                December 2015
                : 32
                : 12
                : 926-932
                Affiliations
                [1 ]Institute of Naval Medicine , Gosport, Hampshire, UK
                [2 ]Office of the Chief Scientist, 59th Medical Wing, Joint Base San Antonio, United States Air Force , San Antonio, Texas, USA
                [3 ]Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine , Birmingham, UK
                [4 ]Academic Unit of Surgery, Glasgow Royal Infirmary , Glasgow, UK
                [5 ]Medical School, University of Campinas , Campinas, Brazil
                [6 ]Department of Anaesthetics, Royal Infirmary of Edinburgh , Edinburgh, UK
                [7 ]Trauma Audit and Research Network, Hope Hospital , Manchester, UK
                [8 ]EMRiS Group, Health Services Research Section, School of Health and Related Research, University of Sheffield , Sheffield, UK
                [9 ]Departments of Surgery and Intensive Care Medicine, Aberdeen Royal Infirmary , Aberdeen, UK
                [10 ]Health Services Research Unit, University of Aberdeen , Aberdeen, UK
                Author notes
                [Correspondence to ] J O Jansen, Departments of Surgery and Intensive Care Medicine, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK; jan.jansen@ 123456nhs.net
                Article
                emermed-2015-205217
                10.1136/emermed-2015-205217
                4717355
                26598631
                7d1bcc66-c991-4fbe-9c62-89f6372832f7
                Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

                This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

                History
                : 12 July 2015
                : 25 October 2015
                : 28 October 2015
                Categories
                1506
                Original Article
                Custom metadata
                unlocked

                Emergency medicine & Trauma
                resuscitation,trauma,trauma, abdomen,trauma, epidemiology,trauma, majot trauma management

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